Tetraethylene glycol

Description

Tetraethylene glycol · CAS 9004-76-6 · C8H18O5. UNII R95B8J264J. Boiling Point: 621 °F at 760 mmHg (USCG, 1999); Boiling Point: 327.3 °C; Boiling Point: 327.3 °C @760 [mm Hg].

Identification

CAS Registry Number	9004-76-6
PubChem CID	8200
Molecular formula	C8H18O5
IUPAC name	2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethanol
UNII (FDA)	R95B8J264J

Computed Descriptors

Molecular Weight	194.23
XLogP3	-1.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	194.11542367
Monoisotopic Mass	194.11542367
Topological Polar Surface Area	68.2
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Boiling Point	621 °F at 760 mmHg (USCG, 1999)
Boiling Point	327.3 °C
Boiling Point	327.3 °C @760 [mm Hg]
Melting Point	24.8 °F (USCG, 1999)
Melting Point	-9.4 °C
Melting Point	-6 °C
Flash Point	360 °F (USCG, 1999)
Flash Point	360 °F (182 °C) (Open cup)
Density	1.1285 g/cu cm at 15 °C
Density	1.1248 @ 20°C

Physical description & handling notes

• Tetraethylene glycol is a colorless to straw-colored liquid with a mild odor. Sinks and mixes with water. (USCG, 1999)
• CBI; Liquid
• Colorless hygroscopic liquid; [Hawley] Colorless to straw colored hygroscopic liquid; [HSDB]
• Liquid
• Colorless liquid
• Colorless to straw-colored liquid

Regulatory Status

Regulatory & Food Contact	FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS POLYOXYETHYLENE(MW 200) CIR / INCI: Cosmetic ingredients (PEG-4) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Solvent; Humectant
GHS notification summary	83% (293 / 353)

GHS Hazard Classification

GHS notification summary	83% (293 / 353)
Reported hazard statements	H319 (17%)

Documented Uses

• Used as a solvent (nitrocellulose, coatings, adhesives, inks, lacquers, lubricants, metalworking fluids, and textile finishes); Also used to extract other solvents, to soften paper tissue, and to make other chemicals; [HSDB] Used as a solvent, extractant, plasticizer, humectant (natural gas), and lubricant (textiles); Also used in cement grinding and brake fluid manufacturing; [Reference #1]
• Metal Machining [Category: Heat or Machine]
• Petroleum Production and Refining [Category: Industry]
• Pulp and Paper Processing [Category: Industry]
• Painting (Pigments, Binders, and Biocides) [Category: Paint]
• Working with Glues and Adhesives [Category: Other]

Synonyms

TETRAETHYLENE GLYCOL; 112-60-7; HI-Dry; 3,6,9-Trioxaundecane-1,11-diol; Carbitol, diethyl; 3,6,9-Trioxaundecan-1,11-diol; DTXSID9026922; Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-; Ethanol, 2,2'-(oxybis(ethyleneoxy))di-; AI3-01838; 2,2'-[oxybis(2,1-ethanediyloxy)]diethanol; Ethanol, 2,2'-(oxybis(2,1-ethanediyloxy))bis-; 2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethan-1-ol; DTXCID806922; 2,2'-[oxybis(ethane-2,1-diyloxy)]diethanol; CHEBI:44920

Frequently Asked Questions

What are the CAS number and molecular formula of Tetraethylene glycol?

CAS 9004-76-6; molecular formula C8H18O5; molecular weight — g/mol.

What other names is Tetraethylene glycol known by?

TETRAETHYLENE GLYCOL, 112-60-7, HI-Dry, 3,6,9-Trioxaundecane-1,11-diol, Carbitol, diethyl, 3,6,9-Trioxaundecan-1,11-diol.

What is the regulatory status of Tetraethylene glycol?

Documented regulatory listings: FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; POLYOXYETHYLENE(MW 200); CIR / INCI: Cosmetic ingredients (PEG-4) -> CIR (Cosmetic Ingredient Review).

Is Tetraethylene glycol classified as hazardous?

83% of GHS notifications report no hazard classification (293 of 353).

What are the key physical properties of Tetraethylene glycol?

Boiling Point: 621 °F at 760 mmHg (USCG, 1999); Boiling Point: 327.3 °C; Boiling Point: 327.3 °C @760 [mm Hg]; Melting Point: 24.8 °F (USCG, 1999).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.