Thiazole

Description

Thiazole is identified by CAS 288-47-1, molecular formula C3H3NS and molecular weight 85.00 g/mol. UNII 320RCW8PEF; ChEBI 43732; InChIKey FZWLAAWBMGSTSO-UHFFFAOYSA-N. Boiling Point: 242.2 °F at 760 mmHg (NTP, 1992); Boiling Point: 115.00 to 118.00 °C. @ 760.00 mm Hg; Boiling Point: 115-118 °C.

Identification

CAS Registry Number	288-47-1
PubChem CID	9256
Molecular formula	C3H3NS
Molecular weight	85.00 g/mol
IUPAC name	1,3-thiazole
InChIKey	FZWLAAWBMGSTSO-UHFFFAOYSA-N
UNII (FDA)	320RCW8PEF
ChEBI ID	CHEBI:43732
FEMA number	3615
JECFA number	1032

Computed Descriptors

Molecular Weight	85.13
XLogP3	0.4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	84.99862027
Monoisotopic Mass	84.99862027
Topological Polar Surface Area	41.1
Heavy Atom Count	5
Formal Charge	0

Physical & Chemical Properties

Boiling Point	242.2 °F at 760 mmHg (NTP, 1992)
Boiling Point	115.00 to 118.00 °C. @ 760.00 mm Hg
Boiling Point	115-118 °C
Density	1.198-1.202
LogP	0.44
Refractive Index	1.531-1.541

Physical description & handling notes

• Thiazole appears as colorless or pale yellow liquid with a foul odor. (NTP, 1992)
• Colorless or light yellow liquid with a foul characteristic odor; [Merck Index] Colorless liquid with an unpleasant odor; [Alfa Aesar MSDS]
• Liquid
• Colourless to pale yellow liquid; green, sweet, nutty, tomatoe note
• Slightly soluble (NTP, 1992)
• Slightly soluble in water; Soluble in ether

Regulatory Status

Regulatory & Food Contact	FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FLAVOURING_AGENT: Flavouring Agent Flavoring Agents Pyridine No safety concern at current levels of intake when used as a flavouring agent TRS 913-JECFA 59/65

GHS Hazard Classification

Reported hazard statements	H225 (86.3%), H226 (13.4%), H302 (100%), H315 (13%), H318 (12.7%), H335 (12.7%)

Documented Uses

• Used as a flavoring agent; [FDA] Used to make fungicides, dyes, and rubber accelerators; [NTP]
• Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
• Flavoring Agents -> JECFA Flavorings Index

Synonyms

THIAZOLE; 288-47-1; 1,3-Thiazole; Thiazoles; FEMA No. 3615; 320RCW8PEF; DTXSID2059776; CHEBI:43732; RefChem:897653; DTXCID4037875; CHEBI:48901; 206-021-3; MFCD00005315; THIAN-4-ONEOXIME; thiazol; CCRIS 3205

Frequently Asked Questions

What are the CAS number and molecular formula of Thiazole?

CAS 288-47-1; molecular formula C3H3NS; molecular weight 85.00 g/mol.

What other names is Thiazole known by?

THIAZOLE, 288-47-1, 1,3-Thiazole, Thiazoles, FEMA No. 3615, 320RCW8PEF.

What is the regulatory status of Thiazole?

Documented regulatory listings: FDA Substance added to food: FLAVORING AGENT OR ADJUVANT; FLAVOURING_AGENT: Flavouring Agent; Flavoring Agents.

Is Thiazole classified as hazardous?

Hazard statements reported: H225, H226, H302, H315, H318.

What are the key physical properties of Thiazole?

Boiling Point: 242.2 °F at 760 mmHg (NTP, 1992); Boiling Point: 115.00 to 118.00 °C. @ 760.00 mm Hg; Boiling Point: 115-118 °C; Density: 1.198-1.202.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.