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Tibolone

CAS 5630-53-5C21H28O2MW 312.4

Tibolone (CAS No. 5630-53-5) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number5630-53-5
Molecular FormulaC21H28O2
Molecular Weight312.4
LogP2.4
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Tibolone?

The CAS number of Tibolone is 5630-53-5.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Tibolone?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Tibolone or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Tibolone · CAS 5630-53-5 · C21H28O2. UNII FF9X0205V2. Solubility: <0.1 g/L.

Identification

CAS Registry Number5630-53-5
PubChem CID444008
Molecular formulaC21H28O2
IUPAC name(7R,8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
UNII (FDA)FF9X0205V2

Computed Descriptors

Molecular Weight312.4
XLogP32.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass312.208930132
Monoisotopic Mass312.208930132
Topological Polar Surface Area37.3
Heavy Atom Count23
Formal Charge0

Physical & Chemical Properties

Solubility<0.1 g/L

Regulatory Status

GHS notification summary1.6% (1 / 63)

GHS Hazard Classification

GHS notification summary1.6% (1 / 63)
Reported hazard statementsH319 (90.5%), H351 (30.2%), H372 (28.6%)

This chemical does not meet GHS hazard criteria for 1.6% (1 of 63) of reports.

H319 (90.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

  • Use (kg; approx.) in Germany (2009): >25
  • Consumption (g per capita; approx.) in Germany (2009): 0.000305
  • For the relief of post-menopausal symptoms and for the prevention of osteoporosis.
  • Tibolone is a synthetic estrogen used for treatment of symptoms of menopause and prevention of osteoporosis. Tibolone has been associated with rare instances of acute, clinically apparent liver injury.
  • Avoid St. John's Wort. St. John's Wort induces CYP3A4, increasing the metabolism of estrogens and progesterone and therefore reducing the efficacy of tibolone.
  • Compounds which inhibit or antagonize the biosynthesis or actions of androgens.

Synonyms

tibolone; 5630-53-5; Liviella; Livial; Org OD 14; Tibolona; Xyvion; Tibolonum; DTXSID5023667; 17-Hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one; ORG-OD 14; FF9X0205V2; NSC-759898; DTXCID103667; CHEBI:32223; 17alpha-ethynyl-17beta-hydroxy-7alpha-methylestr-5(10)-en-3-one

Frequently Asked Questions

What are the CAS number and molecular formula of Tibolone?

CAS 5630-53-5; molecular formula C21H28O2; molecular weight — g/mol.

What other names is Tibolone known by?

tibolone, 5630-53-5, Liviella, Livial, Org OD 14, Tibolona.

Is Tibolone classified as hazardous?

1.6% of GHS notifications report no hazard classification (1 of 63).

What are the key physical properties of Tibolone?

Solubility: <0.1 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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