trimipramine

Description

trimipramine · CAS 739-71-9 · C20H26N2. UNII QJ9MUH57H8. Melting Point: 45; Melting Point: 45 °C; Solubility: 2.60e-02 g/L.

Identification

CAS Registry Number	739-71-9
PubChem CID	5584
Molecular formula	C20H26N2
IUPAC name	3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine
UNII (FDA)	QJ9MUH57H8

Computed Descriptors

Molecular Weight	294.4
XLogP3	5.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	294.209598838
Monoisotopic Mass	294.209598838
Topological Polar Surface Area	6.5
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	45
Melting Point	45 °C
Solubility	2.60e-02 g/L
LogP	4.2
Dissociation Constants	9.24
Dissociation Constants	8.5

Physical description & handling notes

• Solid
• Slightly soluble
• 170.5 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: Antidepressants]
• 169.17 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 171.2 Ų [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]

GHS Hazard Classification

Reported hazard statements	H301 (97.8%), H315 (13%), H317 (13%), H318 (13%), H336 (13%), H400 (13%), H410 (13%)

Documented Uses

• Use (kg) in Switzerland (2009): >750
• Use (kg; approx.) in Germany (2009): >7500
• Consumption (g per capita) in Switzerland (2009): 0.096
• Consumption (g per capita; approx.) in Germany (2009): 0.092
• For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
• Pharmaceuticals -> Nervous System -> Antidepressants

Synonyms

trimipramine; 739-71-9; Trimeprimine; Trimeproprimine; Sapilent; beta-Methylimipramine; Trimeprimina; Trimipramina; Trimipraminum; 7162 RP; IL 6001; IL-6001; 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine; RP-7162; 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine; 6S082C9NDT

Frequently Asked Questions

What are the CAS number and molecular formula of trimipramine?

CAS 739-71-9; molecular formula C20H26N2; molecular weight — g/mol.

What other names is trimipramine known by?

trimipramine, 739-71-9, Trimeprimine, Trimeproprimine, Sapilent, beta-Methylimipramine.

Is trimipramine classified as hazardous?

Hazard statements reported: H301, H315, H317, H318, H336.

What are the key physical properties of trimipramine?

Melting Point: 45; Melting Point: 45 °C; Solubility: 2.60e-02 g/L; LogP: 4.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.