Tris(2-hydroxypropyl)amine

Description

Tris(2-hydroxypropyl)amine · CAS 122-20-3 · C9H21NO3. UNII W9EN9DLM98. Color/Form: Solid at 25 °C; Boiling Point: 581 °F at 760 mmHg (NTP, 1992); Boiling Point: 306 °C.

Identification

CAS Registry Number	122-20-3
PubChem CID	24730
Molecular formula	C9H21NO3
IUPAC name	1-[bis(2-hydroxypropyl)amino]propan-2-ol
UNII (FDA)	W9EN9DLM98

Computed Descriptors

Molecular Weight	191.27
XLogP3	-0.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	191.15214353
Monoisotopic Mass	191.15214353
Topological Polar Surface Area	63.9
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Color/Form	Solid at 25 °C
Boiling Point	581 °F at 760 mmHg (NTP, 1992)
Boiling Point	306 °C
Boiling Point	305 °C
Melting Point	113 °F (NTP, 1992)
Melting Point	45 °C
Flash Point	320 °F (NTP, 1992)
Flash Point	320 °F (160 °C) (Open cup)
Flash Point	160 °C o.c.
Solubility	In water, >1000 g/L at 25 °C

Physical description & handling notes

• Triisopropanolamine is a white solid with slight odor of ammonia. Denser than water.
• Dry Powder; Large Crystals; Liquid; Liquid; CBI; Other Solid
• White hygroscopic solid; [ICSC] Mild ammoniacal odor; [CAMEO] White waxy solid; [MSDSonline]
• WHITE HYGROSCOPIC CRYSTALS.
• Crystalline, white solid
• Soluble (NTP, 1992)

Regulatory Status

Regulatory & Food Contact

FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS Di-(para-methylbenzylidene) sorbitol (CAS Reg. No. 81541-12-0, 54686-97-4 and 197809-37-3) alone or containing As a clarifying agent for polypropylene homopolymers and copolymers complying with 21 CFR 177.1520. For use at levels not to exceed 0.32 percent by weight of the finished polymer under Conditions of Use B throu

GHS notification summary

0.1% (1 / 1735)

GHS Hazard Classification

GHS notification summary	0.1% (1 / 1735)
Reported hazard statements	H319, H412 (66.9%), H318, H335, H336, H315

Documented Uses

• CIR ingredient: Triisopropanolamine
• Metal Machining [Category: Heat or Machine]
• Electroplating [Category: Plate]
• Painting (Pigments, Binders, and Biocides) [Category: Paint]
• Crosslinking agent (rubber); emulsifier/corrosion inhibitor (metal working fluids); surfactant/solubilising agent
• Color stabilizer for polyethylene formulations

Synonyms

Triisopropanolamine; 122-20-3; TIPA; TRIS(2-HYDROXYPROPYL)AMINE; Tri-2-propanolamine; Tri-iso-propanolamine; Tris(2-propanol)amine; Tris(2-hydroxy-1-propyl)amine; 2-Propanol, 1,1',1''-nitrilotri-; 2-Propanol, 1,1',1''-nitrilotris-; 1,1',1''-Nitrilotri-2-propanol; DTXSID5021415; Triisopropanolamin; W9EN9DLM98; 1,1',1''-Nitrilotris(2-propanol); UNICHEM TIPA

Frequently Asked Questions

What are the CAS number and molecular formula of Tris(2-hydroxypropyl)amine?

CAS 122-20-3; molecular formula C9H21NO3; molecular weight — g/mol.

What other names is Tris(2-hydroxypropyl)amine known by?

Triisopropanolamine, 122-20-3, TIPA, TRIS(2-HYDROXYPROPYL)AMINE, Tri-2-propanolamine, Tri-iso-propanolamine.

What is the regulatory status of Tris(2-hydroxypropyl)amine?

Documented regulatory listings: FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS.

Is Tris(2-hydroxypropyl)amine classified as hazardous?

0.1% of GHS notifications report no hazard classification (1 of 1735).

What are the key physical properties of Tris(2-hydroxypropyl)amine?

Color/Form: Solid at 25 °C; Boiling Point: 581 °F at 760 mmHg (NTP, 1992); Boiling Point: 306 °C; Boiling Point: 305 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.