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Description

Ulobetasol · CAS 98651-66-2 · C22H27ClF2O4. UNII 9P6159HM7T. Melting Point: 200-216.

Identification

CAS Registry Number	98651-66-2
PubChem CID	5311167
Molecular formula	C22H27ClF2O4
IUPAC name	(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
UNII (FDA)	9P6159HM7T

Computed Descriptors

Molecular Weight	428.9
XLogP3	2.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	428.1565934
Monoisotopic Mass	428.1565934
Topological Polar Surface Area	74.6
Heavy Atom Count	29
Formal Charge	0

Physical & Chemical Properties

Melting Point	200-216

Physical description & handling notes

• Practically insoluble

Documented Uses

• Ulobetasol cream and ointment are indicated in the treatment of inflammatory and pruritic corticosteroid responsive dermatoses. Ulobetasol lotion is indicated in the treatment of plaque psoriasis.
• Drugs used to cause constriction of the blood vessels.
• Established Pharmacologic Class [EPC] - Corticosteroid
• Mechanisms of Action [MoA] - Corticosteroid Hormone Receptor Agonists
• Halobetasol is a Corticosteroid. The mechanism of action of halobetasol is as a Corticosteroid Hormone Receptor Agonist.
• D07 - Corticosteroids, dermatological preparations

Synonyms

Halobetasol; Ulobetasol; 98651-66-2; 21-chloro diflorasone; 9P6159HM7T; CGP 14458; DTXSID60243759; IDP-122; 21-CHLORO-6alpha,9-DIFLUORO-11beta,17-DIHYDROXY-16beta-METHYLPREGNA-1,4-DIENE-3,20-DIONE; Ulobetasolum; RefChem:58664; D07AC21; DTXCID40166250; Ulobetasol [INN]; UNII-9P6159HM7T; Halobetasol [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of Ulobetasol?

CAS 98651-66-2; molecular formula C22H27ClF2O4; molecular weight — g/mol.

What other names is Ulobetasol known by?

Halobetasol, Ulobetasol, 98651-66-2, 21-chloro diflorasone, 9P6159HM7T, CGP 14458.

What are the key physical properties of Ulobetasol?

Melting Point: 200-216.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.