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Description

Uric acid · CAS 69-93-2 · C5H4N4O3. UNII 268B43MJ25. Melting Point: Greater than 300 °C; Melting Point: > 300 °C; Solubility: 60.

Identification

CAS Registry Number	69-93-2
PubChem CID	1175
Molecular formula	C5H4N4O3
IUPAC name	7,9-dihydro-3H-purine-2,6,8-trione
UNII (FDA)	268B43MJ25

Computed Descriptors

Molecular Weight	168.11
XLogP3	-1.9
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	168.02834000
Monoisotopic Mass	168.02834000
Topological Polar Surface Area	99.3
Heavy Atom Count	12
Formal Charge	0

Physical & Chemical Properties

Melting Point	Greater than 300 °C
Melting Point	> 300 °C
Solubility	60
Solubility	0.06 mg/mL
LogP	-2.17
Dissociation Constants	5.4
Collision Cross Section	142.6 Ų [M+Na]+
Collision Cross Section	126.2 Ų [M-H]-
Collision Cross Section	130.5 Ų [M+H]+

Physical description & handling notes

• White odorless solid; [Merck Index] Beige powder; [Sigma-Aldrich MSDS]
• Solid
• 126.4 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID3042508]
• 126.93 Ų [M-H]- [CCS Type: DT; Method: stepped-field]
• 127.08 Ų [M-H]- [CCS Type: DT; Method: stepped-field]
• 143.5 Ų [M+Na]+ [CCS Type: DT; Method: stepped-field]

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Buffering; Skin conditioning
GHS notification summary	96.8% (30 / 31)

GHS Hazard Classification

GHS notification summary	96.8% (30 / 31)

Documented Uses

• Cosmetics -> Buffering; Skin conditioning
• 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-: ACTIVE
• At present (August 2013), there is no approved indication for uric acid. The potential therapeutic use for uric acid is as an adjunct in acute ischemic stroke.
• Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
• Uric acid is eliminated by the kidneys.
• In higher primates and humans, the enzyme, uricase, is absent, and thus uric acid is not further metabolized and is excreted. In all other mammals, uric acid is metabolized by uricase to allantoin, which is then excreted.

Synonyms

uric acid; 69-93-2; urate; Lithic acid; 2,6,8-trioxypurine; 2,6,8-trihydroxypurine; 7,9-Dihydro-1H-purine-2,6,8(3H)-trione; 2,6,8-Trioxopurine; 1H-Purine-2,6,8-triol; 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-; Purine-2,6,8(1H,3H,9H)-trione; 7,9-dihydro-3H-purine-2,6,8-trione; 2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione; Uricum acidum; Idelalisib metabolite m54; trioxopurine

Frequently Asked Questions

What are the CAS number and molecular formula of Uric acid?

CAS 69-93-2; molecular formula C5H4N4O3; molecular weight — g/mol.

What other names is Uric acid known by?

uric acid, 69-93-2, urate, Lithic acid, 2,6,8-trioxypurine, 2,6,8-trihydroxypurine.

What is the regulatory status of Uric acid?

Documented regulatory listings: CIR / INCI: Buffering; Skin conditioning.

Is Uric acid classified as hazardous?

96.8% of GHS notifications report no hazard classification (30 of 31).

What are the key physical properties of Uric acid?

Melting Point: Greater than 300 °C; Melting Point: > 300 °C; Solubility: 60; Solubility: 0.06 mg/mL.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.