Velpatasvir intermediate A13

Name: Velpatasvir intermediate A13
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 1377049-84-7C49H54N8O8MW 883.0

Velpatasvir intermediate A13 (CAS No. 1377049-84-7) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1377049-84-7

Molecular FormulaC49H54N8O8

Molecular Weight883.0

LogP6.2

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsOrganic Chemicals

CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Velpatasvir intermediate A13?

The CAS number of Velpatasvir intermediate A13 is 1377049-84-7.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Velpatasvir intermediate A13?

Main applications include Organic Chemicals.

How do I buy Velpatasvir intermediate A13 or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Velpatasvir intermediate A13 · CAS 1377049-84-7 · C49H54N8O8. UNII KCU0C7RS7Z.

Identification

CAS Registry Number	1377049-84-7
PubChem CID	67683363
Molecular formula	C49H54N8O8
UNII (FDA)	KCU0C7RS7Z

Computed Descriptors

Molecular Weight	883.0
XLogP3	6.2
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	13
Exact Mass	882.40646071
Monoisotopic Mass	882.40646071
Topological Polar Surface Area	193
Heavy Atom Count	65
Formal Charge	0

Physical description & handling notes

Velpatasvir is a small molecule direct-acting antiviral used in the treatment of hepatitis C in combination with sofosbuvir. Velpatasvir prevents viral replication by inhibiting non-structural protein 5A (NS5A). At a dose 5 times the recommended dose, velpatasvir does not prolong QTc interval to any clinically relevant extent.

Regulatory Status

GHS notification summary	50% (1 / 2)

GHS Hazard Classification

GHS notification summary	50% (1 / 2)
Reported hazard statements	H413 (50%), H410 (100%)

This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.

H413 (50%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

Documented Uses

Breast Feeding; Lactation; Milk, Human; Antiviral Agents; NS5A Inhibitors
Take with or without food. Multiple different combination products contain velpatasvir. Take Epclusa with or without food. Take Vosevi with food.
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Established Pharmacologic Class [EPC] - Hepatitis C Virus NS5A Inhibitor
Mechanisms of Action [MoA] - Breast Cancer Resistance Protein Inhibitors
Mechanisms of Action [MoA] - P-Glycoprotein Inhibitors

Synonyms

Velpatasvir; 1377049-84-7; GS-5816; GS5816; KCU0C7RS7Z; GS 5816; CHEBI:133009; DTXSID70722565; EPCLUSA COMPONENT VELPATASVIR; velpatasvirum; RefChem:901782; DTXCID401513466; MFCD28411371; Velpatasvir R Isomer (Imidazole); UNII-KCU0C7RS7Z; Velpatasvir [USAN:INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Velpatasvir intermediate A13?

CAS 1377049-84-7; molecular formula C49H54N8O8; molecular weight — g/mol.

What other names is Velpatasvir intermediate A13 known by?

Velpatasvir, 1377049-84-7, GS-5816, GS5816, KCU0C7RS7Z, GS 5816.

Is Velpatasvir intermediate A13 classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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