Vilazodone

Description

Vilazodone · CAS 163521-12-8 · C26H27N5O2. UNII S239O2OOV3. Solubility: 1.23e-01 g/L.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• Solid from ethyl acetate
• MP: 227-279 °C /Vilazodone hydrochloride/
• Stable under normal handling conditions. /Vilazodone hydrochloride/
• May emit toxic gasses like Carbon monoxide, Carbon dioxide, Nitrogen oxides upon thermal decomposition. /Vilazodone hydrochloride/
• 212.9 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: Antidepressants]

Documented Uses

• Preparation: H. Bottcher et al., German patent 4333254; eidem, United States of America patent 5532241 (1995, 1996 both to Merck Patent GmbH).
• From hydrochloride-saturated 2-propanol /Vilazodone hydrochloride/
• Vilazodone is approved for treatment of major depressive disorder.
• Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist which is used in the therapy of major depressive disorders. In premarketing clinical trials, vilazodone therapy was not associated with an increased rate of elevations in serum aminotransferase levels, and it has yet to be linked to instances of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antidepressive Agents; Serotonin Uptake Inhibitors
• Vilazodone (Class: Antidepressants, Added Date: 11-2012)

Synonyms

Vilazodone; 163521-12-8; 5-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide; vilazodona; EMD 515259; vilazodonum; 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide; 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide; EMD-515259; EMD-68-843; EMD 68843 BASE; S239O2OOV3; CHEBI:70707; DTXSID80870086; 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide; 5-(4-(4-(5-Cyanoindol-3-yl)butyl)-1-piperazinyl)-2-benzofurancarboxamide

Frequently Asked Questions

What are the CAS number and molecular formula of Vilazodone?

CAS 163521-12-8; molecular formula C26H27N5O2; molecular weight — g/mol.

What other names is Vilazodone known by?

Vilazodone, 163521-12-8, 5-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide, vilazodona, EMD 515259, vilazodonum.

What are the key physical properties of Vilazodone?

Solubility: 1.23e-01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.