Vortioxetine

Description

Vortioxetine · CAS 508233-74-7 · C18H22N2S. UNII 3O2K1S3WQV.

Identification

Computed Descriptors

Physical description & handling notes

• stable if stored as directed /Vortioxetine hydrobromide/
• Thermal decomposition may produce toxic gases such as carbon monoxide, carbon dioxide, and nitrogen oxides. /Vortioxetine hydrobromide/
• White to very slightly beige powder; slightly soluble in water /Vortioxetine hydrogen bromide/
• Oral: 5 mg, 10 mg, and 20 mg tablets, Trintellix /Vortioxetine hydrobromide/
• Table: Vortioxetine Hydrobromide Preparations [Table#8230]

GHS Hazard Classification

Documented Uses

• Anti-Anxiety Agents; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Uptake Inhibitors
• Vortioxetine is indicated for the treatment of major depressive disorder (MDD).
• Vortioxetine is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment, but has not been linked to instances of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antidepressive Agents; Serotonin Uptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Antagonists
• Vortioxetine (Class: Antidepressants, Added Date: 10-2016)
• Brintellix is indicated for the treatment of major depressive disorder (MDD). The efficacy of Brintellix was established in six 6 to 8 week studies (including one study in the elderly) and one maintenance study in adults. /Included in US product label/

Synonyms

VORTIOXETINE; 508233-74-7; Lu AA21004; vortioxetina; 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine; vortioxetinum; 3O2K1S3WQV; LuAA21004; Lu-AA21004; Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-; CHEBI:76016; DTXSID80965062; Piperazine, 1-(2-((2,4-dimethylphenyl)thio)phenyl)-; 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine; 1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine; 1-(2-((2,4-Dimethylphenyl)sulfanyl)phenyl}piperazine

Frequently Asked Questions

What are the CAS number and molecular formula of Vortioxetine?

CAS 508233-74-7; molecular formula C18H22N2S; molecular weight — g/mol.

What other names is Vortioxetine known by?

VORTIOXETINE, 508233-74-7, Lu AA21004, vortioxetina, 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine, vortioxetinum.

Is Vortioxetine classified as hazardous?

Hazard statements reported: H302, H361, H371, H373, H400.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.