亚甲基蓝

Description

Methylene Blue trihydrate is identified by CAS 7220-79-3, molecular formula C16H24ClN3O3S and molecular weight 373.12 g/mol. UNII T42P99266K; InChIKey XQAXGZLFSSPBMK-UHFFFAOYSA-M.

Identification

CAS Registry Number	7220-79-3
PubChem CID	104827
Molecular formula	C16H24ClN3O3S
Molecular weight	373.12 g/mol
IUPAC name	[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
InChIKey	XQAXGZLFSSPBMK-UHFFFAOYSA-M
UNII (FDA)	T42P99266K

Computed Descriptors

Molecular Weight	373.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
Exact Mass	373.1226905
Monoisotopic Mass	373.1226905
Topological Polar Surface Area	46.9
Heavy Atom Count	24
Formal Charge	0
Complexity	483

Physical description & handling notes

• Methylene blue trihydrate appears as odorless or almost odorless dark green crystals with bronze luster or dark green crystalline powder. pH (1% solution in water) 3 to 4.5. (NTP, 1992)
• Dark green odorless solid with a bronze luster; [Merck Index] Hygroscopic; [CAMEO] Dark green powder; [Sigma-Aldrich MSDS]
• 374 °F (decomposes) (NTP, 1992)
• greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)

Regulatory Status

GHS notification summary	7.6% (7 / 92)

GHS Hazard Classification

GHS notification summary	7.6% (7 / 92)
Reported hazard statements	H302 (92.4%), H315 (48.9%), H319 (71.7%), H335 (46.7%), H373 (22.8%)

Documented Uses

• Used as a bacteriological stain, redox colorimetric agent, and in medicine (antimethemoglobinic); [Merck Index] Used to dye cotton and wool; [NTP]
• Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
• Information on 2 consumer products that contain Methylene blue in the following categories is provided:

Synonyms

Methylene Blue trihydrate; 7220-79-3; Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride, trihydrate; DTXSID0025600; 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate; Methylene blue (USP); C.I. Basic Blue 9, trihydrate; CCRIS 9312; UNII-T42P99266K; Methylene blue [USP]; DTXCID705600; METHYLENE BLUE TRIHYDRATE [MI]; NSC 759135; C.I. Basic Blue 9, trihydrate (8CI); RefChem:158183; METHYLTHIONINE TRIHYDRATE

Frequently Asked Questions

What are the CAS number and molecular formula of Methylene Blue trihydrate?

CAS 7220-79-3; molecular formula C16H24ClN3O3S; molecular weight 373.12 g/mol.

What other names is Methylene Blue trihydrate known by?

Methylene Blue trihydrate, 7220-79-3, Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride, trihydrate, DTXSID0025600, 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate, Methylene blue (USP).

Is Methylene Blue trihydrate classified as hazardous?

7.6% of GHS notifications report no hazard classification (7 of 92).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.