Ethyl 4-hydroxybenzoate

Description

Ethyl 4-hydroxybenzoate is identified by CAS 120-47-8, molecular formula C9H10O3 and molecular weight 166.06 g/mol. UNII 14255EXE39; ChEBI 31575; InChIKey NUVBSKCKDOMJSU-UHFFFAOYSA-N. Boiling Point: 297-298 °C (decomposition); Boiling Point: 298.00 °C. @ 760.00 mm Hg; Melting Point: 117 °C.

Identification

CAS Registry Number	120-47-8
PubChem CID	8434
Molecular formula	C9H10O3
Molecular weight	166.06 g/mol
IUPAC name	ethyl 4-hydroxybenzoate
InChIKey	NUVBSKCKDOMJSU-UHFFFAOYSA-N
UNII (FDA)	14255EXE39
ChEBI ID	CHEBI:31575

Computed Descriptors

Molecular Weight	166.17
XLogP3	2.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	166.062994177
Monoisotopic Mass	166.062994177
Topological Polar Surface Area	46.5
Heavy Atom Count	12
Formal Charge	0

Physical & Chemical Properties

Boiling Point	297-298 °C (decomposition)
Boiling Point	298.00 °C. @ 760.00 mm Hg
Melting Point	117 °C
Melting Point	116 °C
Solubility	In water, 8.85X10+2 mg/L at 25 °C
Solubility	AT 25 °C: 0.5 G/100 G GLYCERIN
Solubility	0.885 mg/mL at 25 °C
Vapor Pressure	0.0000929 [mmHg]
LogP	log Kow = 2.47
LogP	2.47

Physical description & handling notes

• Liquid; Other Solid
• Almost odourless, small, colourless crystals or a white, crystalline powder
• Colorless solid; [Hawley] Crystalline powder; [MSDSonline]
• Solid
• Small, colorless crystals or powder at room temperature
• Crystals from dilute alcohol

Regulatory Status

Regulatory & Food Contact	EU Flavoring substances FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS Flavoring Agents PRESERVATIVE: Food Additives JECFA ADI: 0-10 mg/kg bw Group ADI as the sum of the ethyl and methyl esters of p-hydroxybenzoic acid. In view of the adverse effects i
GHS notification summary	60.7% (811 / 1336)

GHS Hazard Classification

GHS notification summary	60.7% (811 / 1336)
Reported hazard statements	H304 (33.5%), H315 (38.8%), H317 (34%), H319 (39.3%), H401

Documented Uses

• Used as a preservative for pharmaceuticals, adhesives, and various cosmetic preparations (inhibits fungal and bacterial growth); [HSDB] The parabens (methyl, ethyl, propyl, and butyl) were the most widely used preservatives in cosmetics (0.1% to 0.8%) until their sensitizing potential was recognized; [Marks, p. 115]
• Working with Glues and Adhesives [Category: Other]
• Antimicrobial preservative for pharmaceuticals.
• Ethyl paraben ... inhibits the growth of fungi and bacteria and is used as a preservative for pharmaceuticals, adhesives, and various cosmetic preparations.
• ... Antibacterials that prevent /food spoilage by/ Clostridium botulinum include ... parabens ... /Parabens/
• Ethylparaben is found in alcoholic beverages.

Synonyms

Ethylparaben; ETHYL 4-HYDROXYBENZOATE; 120-47-8; Ethyl paraben; Ethyl p-hydroxybenzoate; Tegosept E; Mycocten; Ethyl parasept; 4-Hydroxybenzoic acid ethyl ester; Aseptoform E; Nipagin A; Easeptol; Ethyl butex; Napagin A; Nipazin A; Solbrol A

Frequently Asked Questions

What are the CAS number and molecular formula of Ethyl 4-hydroxybenzoate?

CAS 120-47-8; molecular formula C9H10O3; molecular weight 166.06 g/mol.

What other names is Ethyl 4-hydroxybenzoate known by?

Ethylparaben, ETHYL 4-HYDROXYBENZOATE, 120-47-8, Ethyl paraben, Ethyl p-hydroxybenzoate, Tegosept E.

What is the regulatory status of Ethyl 4-hydroxybenzoate?

Documented regulatory listings: EU Flavoring substances; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; Flavoring Agents.

Is Ethyl 4-hydroxybenzoate classified as hazardous?

60.7% of GHS notifications report no hazard classification (811 of 1336).

What are the key physical properties of Ethyl 4-hydroxybenzoate?

Boiling Point: 297-298 °C (decomposition); Boiling Point: 298.00 °C. @ 760.00 mm Hg; Melting Point: 117 °C; Melting Point: 116 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.