丙二醇

Description

1,2-Propanediol is identified by CAS 57-55-6, molecular formula C3H8O2 and molecular weight 76.05 g/mol. UNII 6DC9Q167V3; ChEBI 16997; InChIKey DNIAPMSPPWPWGF-UHFFFAOYSA-N. Boiling Point: 370.8 °F at 760 mmHg (NTP, 1992); Boiling Point: 187.6; Boiling Point: 187.6 °C.

Identification

CAS Registry Number	57-55-6
PubChem CID	1030
Molecular formula	C3H8O2
Molecular weight	76.05 g/mol
IUPAC name	propane-1,2-diol
InChIKey	DNIAPMSPPWPWGF-UHFFFAOYSA-N
UNII (FDA)	6DC9Q167V3
ChEBI ID	CHEBI:16997
FEMA number	2940
JECFA number	925

Computed Descriptors

Molecular Weight	76.09
XLogP3	-0.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	76.052429494
Monoisotopic Mass	76.052429494
Topological Polar Surface Area	40.5
Heavy Atom Count	5
Formal Charge	0

Physical & Chemical Properties

Boiling Point	370.8 °F at 760 mmHg (NTP, 1992)
Boiling Point	187.6
Boiling Point	187.6 °C
Boiling Point	188.2 °C
Boiling Point	370.8 °F
Boiling Point	187.6 °C @760 [mm Hg]
Melting Point	-76 °F (NTP, 1992)
Melting Point	-60
Melting Point	-60 °C
Melting Point	-59 °C

Physical description & handling notes

• Thick odorless colorless liquid. Mixes with water. (USCG, 1999)
• Large Crystals; CBI; Liquid; Wet Solid; Other Solid; Liquid; Liquid; Other Solid
• Clear, colourless, hygroscopic, viscous liquid
• Clear, colorless, viscous liquid; [ChemIDplus]
• COLOURLESS ODOURLESS HYGROSCOPIC VISCOUS LIQUID.
• Thick odorless colorless liquid.

Regulatory Status

Regulatory & Food Contact

FDA Substance added to food: ANTICAKING AGENT OR FREE-FLOW AGENT, ANTIMICROBIAL AGENT, ANTIOXIDANT, DRYING AG FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS CARRIER_SOLVENT; GLAZING_AGENT; HUMECTANT: Food Additives ANTICAKING AGENT OR FREE-FLOW AGENT, ANTIMICROBIAL AGENT, ANTIOXIDANT, DRYING AGENT, EMULSIFIER OR EMULSIFIER JECFA ADI: 0-25 mg/kg bw (1973)

GHS notification summary

98% (6762 / 6899)

GHS Hazard Classification

GHS notification summary	98% (6762 / 6899)
Reported hazard statements	H336, H370, H372

Documented Uses

• CIR ingredient: Propylene Glycol
• Used in antifreeze and deicing solutions for cars, boats, and aircraft; also used as a solvent for paints and plastics and to create harmless, artificial smoke for training and theatrical purposes; [ATSDR ToxFAQs]
• Painting (Solvents) [Category: Paint]
• Photographic Processing [Category: Other]
• Propylene glycol is used as a skin-conditioning agent-humectant, solvent, viscosity-decreasing agent, and humectant in cosmetic formulations.
• For more Uses (Complete) data for Propylene glycol (29 total), please visit the HSDB record page.

Synonyms

propylene glycol; 1,2-propanediol; 57-55-6; propane-1,2-diol; 1,2-Propylene glycol; 1,2-dihydroxypropane; 2-Hydroxypropanol; Isopropylene glycol; Dowfrost; Sirlene; Methylethyl glycol; Methylethylene glycol; Monopropylene glycol; Trimethyl glycol; Propylene Glycol USP; Solar Winter BAN

Frequently Asked Questions

What are the CAS number and molecular formula of 1,2-Propanediol?

CAS 57-55-6; molecular formula C3H8O2; molecular weight 76.05 g/mol.

What other names is 1,2-Propanediol known by?

propylene glycol, 1,2-propanediol, 57-55-6, propane-1,2-diol, 1,2-Propylene glycol, 1,2-dihydroxypropane.

What is the regulatory status of 1,2-Propanediol?

Documented regulatory listings: FDA Substance added to food: ANTICAKING AGENT OR FREE-FLOW AGENT, ANTIMICROBIAL AGENT, ANTIOXIDANT, DRYING AG; FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS.

Is 1,2-Propanediol classified as hazardous?

98% of GHS notifications report no hazard classification (6762 of 6899).

What are the key physical properties of 1,2-Propanediol?

Boiling Point: 370.8 °F at 760 mmHg (NTP, 1992); Boiling Point: 187.6; Boiling Point: 187.6 °C; Boiling Point: 188.2 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.