环己基氨基磺酸半钙

Description

cyclamic acid hemicalcium · CAS 139-06-0 · C12H24CaN2O6S2. UNII X12LMJ1WYL.

Identification

CAS Registry Number	139-06-0
PubChem CID	8752
Molecular formula	C12H24CaN2O6S2
IUPAC name	calcium bis(N-cyclohexylsulfamate)
UNII (FDA)	X12LMJ1WYL

Computed Descriptors

Molecular Weight	396.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	2
Exact Mass	396.0701697
Monoisotopic Mass	396.0701697
Topological Polar Surface Area	155
Heavy Atom Count	23
Formal Charge	0
Complexity	187

Physical description & handling notes

• Solid; [HSDB]
• Crystalline solid
• Strong, sweet taste
• Form: crystals; pleasant, very sweet taste; practically insol in alcohol, benzene, chloroform, ether; pH of 10% aq soln 5.5-7.5; Said to be more resistant to cooking temp than saccharin /Dihydrate/
• ODORLESS; WHITE CRYSTALLINE POWDER; 1 G SOL IN 4 ML WATER; 1 G SOL IN 60 ML ETHANOL; 1 G SOL IN 1.5 ML PROPYLENE GLYCOL; LOSS ON DRYING @ 140 °C FOR 2 HR 9.0% MAX /DIHYDRATE/; IN DILUTE SOLN ABOUT 30 TIMES AS SWEET AS SUCROSE
• SOL IN AQ SOLN OF SORBITOL; 25 G SOL IN 100 ML 25% ALCOHOL; 2.4 G SOL IN 100 ML 90% ETHYL ALCOHOL

Regulatory Status

Regulatory & Food Contact	SWEETENER: Food Additives JECFA ADI: 0-11 mg/kg bw Cyclamates ADI expressed as cyclamic acid TRS 683-JECFA 26/27 FAS 17-JECFA 26/66
GHS notification summary	10.7% (6 / 56)

GHS Hazard Classification

GHS notification summary	10.7% (6 / 56)
Reported hazard statements	H315 (89.3%), H319 (89.3%), H335 (89.3%)

Documented Uses

• Used as a non-caloric sweetener in foods; [HSDB]
• Cyclamates: Banned by the FDA for use in foods in 1970 (also banned in many other countries); [HSDB]
• FORMERLY AS A NONCALORIC SWEETENER IN BEVERAGES & FOOD PRODUCTS
• Food Additives -> SWEETENER -> JECFA Functional Classes
• Cummins, Johnson; McQuaid, US patents 2,799,700; 2,804,477 (both 1957 to Du Pont); Freifelder, US patent 3,082,247 (1963 to Abbott); Birsten, Rosin, US patents 3,361,798; 3,366,670 (both 1968 to Baldwin-Montrose).
• ...BY NEUTRALIZING CYCLAMIC ACID WITH...CALCIUM HYDROXIDE...OR BY SULFONATION OF CYCLOHEXYLAMINE WITH...CALCIUM SULFAMATE.

Synonyms

CALCIUM CYCLAMATE; 139-06-0; Cyclamate calcium; Cyclan; Dietil; Cylan; Sucaryl calcium; Calcium cyclohexanesulfamate; Kalziumzyklamate; Cyclamate, calcium salt; Calcium cyclohexylsulphamate; Calcium cyclohexane sulphamate; X12LMJ1WYL; Calcium cyclamate anhydrous; Calcium cyclohexylsulfamate (1:2); Cyclohexanesulfamic acid, calcium salt (2:1)

Frequently Asked Questions

What are the CAS number and molecular formula of cyclamic acid hemicalcium?

CAS 139-06-0; molecular formula C12H24CaN2O6S2; molecular weight — g/mol.

What other names is cyclamic acid hemicalcium known by?

CALCIUM CYCLAMATE, 139-06-0, Cyclamate calcium, Cyclan, Dietil, Cylan.

What is the regulatory status of cyclamic acid hemicalcium?

Documented regulatory listings: SWEETENER: Food Additives; JECFA ADI: 0-11 mg/kg bw; Cyclamates ADI expressed as cyclamic acid.

Is cyclamic acid hemicalcium classified as hazardous?

10.7% of GHS notifications report no hazard classification (6 of 56).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.