一水肌酸

Description

Creatine Monohydrate · CAS 6020-87-7 · C4H9N3O2. UNII MU72812GK0. Melting Point: 255; Melting Point: Decomposes at 303 °C; Melting Point: 303 °C.

Identification

CAS Registry Number	6020-87-7
PubChem CID	586
Molecular formula	C4H9N3O2
IUPAC name	2-[carbamimidoyl(methyl)amino]acetic acid
UNII (FDA)	MU72812GK0

Computed Descriptors

Molecular Weight	131.13
XLogP3	-1.2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	131.069476538
Monoisotopic Mass	131.069476538
Topological Polar Surface Area	90.4
Heavy Atom Count	9
Formal Charge	0

Physical & Chemical Properties

Melting Point	255
Melting Point	Decomposes at 303 °C
Melting Point	303 °C
Solubility	13300
Solubility	In water, 1.33X10+4 mg/L at 18 °C
Solubility	13.3 mg/mL at 18 °C
Density	1.33 at 25 °C
Vapor Pressure	0.00079 [mmHg]
LogP	-0.2
Dissociation Constants	pKb = 11.02 at 20 °C

Physical description & handling notes

• Solid; [Merck Index] White powder; [Alfa Aesar MSDS]
• Solid
• Slightly soluble in water, insoluble in ether
• Slightly soluble in ether and ethanol
• Neutral reaction to litmus
• pKa1 = 3.8 (carboxylic acid); pKa2 = 12.7 (amine)

Regulatory Status

Regulatory & Food Contact	Creatine supplements: The basics
GHS notification summary	72.3% (149 / 206)

GHS Hazard Classification

GHS notification summary	72.3% (149 / 206)
Reported hazard statements	H315 (27.7%), H319 (27.7%), H335 (27.7%)

Documented Uses

• An amino acid found mainly in skeletal and cardiac muscle; Involved in the transfer of high energy phosphate in muscle cells; [Merck Index] Used in the diagnosis of myocardial dysfunction and as a dietary supplement to enhance athletic performance; [HSDB]
• Used in diagnosis of myocardial disfunction; dietary supplement for exercise performance
• For nutritional supplementation, also for treating dietary shortage or imbalance
• Information on 3 consumer products that contain Creatine in the following categories is provided:
• Monosubstituted and N,N-disubstituted compounds, including guanidinocarboxylic acids (eg, creatine), are produced industrially by the reaction of cyanamide with the corresponding amines or aminocarboxylic acids.
• Glycine, N-(aminoiminomethyl)-N-methyl-: ACTIVE

Synonyms

creatine; 57-00-1; Creatin; N-amidinosarcosine; Kreatin; Krebiozon; methylglycocyamine; N-methyl-N-guanylglycine; Glycine, N-(aminoiminomethyl)-N-methyl-; Pyrolysate; (alpha-Methylguanido)acetic acid; N-carbamimidoyl-N-methylglycine; Cosmocair C 100; Kreatinum; Neotine; 2-(1-methylcarbamimidamido)acetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Creatine Monohydrate?

CAS 6020-87-7; molecular formula C4H9N3O2; molecular weight — g/mol.

What other names is Creatine Monohydrate known by?

creatine, 57-00-1, Creatin, N-amidinosarcosine, Kreatin, Krebiozon.

What is the regulatory status of Creatine Monohydrate?

Documented regulatory listings: Creatine supplements: The basics;

Is Creatine Monohydrate classified as hazardous?

72.3% of GHS notifications report no hazard classification (149 of 206).

What are the key physical properties of Creatine Monohydrate?

Melting Point: 255; Melting Point: Decomposes at 303 °C; Melting Point: 303 °C; Solubility: 13300.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.