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Azilsartan

CAS 147403-03-0C25H20N4O5MW 456.4

Azilsartan (CAS No. 147403-03-0) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number147403-03-0
Molecular FormulaC25H20N4O5
Molecular Weight456.4
Melting Point212-214 °C
LogPlog Kow = 0.90
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Azilsartan?

The CAS number of Azilsartan is 147403-03-0.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Azilsartan?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Azilsartan or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Azilsartan · CAS 147403-03-0 · C25H20N4O5. UNII F9NUX55P23. Melting Point: 212-214 °C; LogP: log Kow = 0.90.

Identification

CAS Registry Number147403-03-0
PubChem CID135415867
Molecular formulaC25H20N4O5
IUPAC name2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
UNII (FDA)F9NUX55P23

Computed Descriptors

Molecular Weight456.4
XLogP34.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass456.14336975
Monoisotopic Mass456.14336975
Topological Polar Surface Area115
Heavy Atom Count34
Formal Charge0

Physical & Chemical Properties

Melting Point212-214 °C
LogPlog Kow = 0.90

Physical description & handling notes

  • Colorless prisms from ethanol
  • Stable under recommended storage conditions.
  • Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx).
  • pKa at 0.1 N NaOH (26 eg C): 6.1
  • Crystals from ethanol /Azilsartan medoxomil/
  • Crystals; mp 196 °C (decomposes). Freely soluble in methanol. Practically insolluble in water /Azilsartan kamedoxomil/

GHS Hazard Classification

Reported hazard statementsH360 (25%), H361 (75%), H362 (25%), H372 (25%)

H360 (25%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H361 (75%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Preparation: T. Naka, Y. Inada, European Patent Office patent 0520423; eidem, United States of America patent 5243054 (1992, 1993 both to Takeda).
  • United States Food and Drug Administration–Approved Indications
  • Azilsartan is an angiotensin II receptor blocker (ARB) used in the therapy of hypertension. It is associated with a low rate of transient serum aminotransferase elevations, but has yet to be linked to instances of acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Blockers
  • Angiotensin II Receptor Antagonists
  • Edarbi is an angiotensin II receptor blocker (ARB) indicated for the treatment of hypertension to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including the class to which this drug principally belongs. /Included in US product label/

Synonyms

Azilsartan; 147403-03-0; TAK-536; TAK 536; F9NUX55P23; 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid; CHEBI:68850; DTXSID70163712; 2-ethoxy-3-((4-(2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl)phenyl)methyl)benzimidazole-4-carboxylic acid; RefChem:54400; DTXCID1086203; Azilsartan [USAN]; AZILSARTAN [INN]; MFCD20278186; C25H20N4O5; CHEMBL57242

Frequently Asked Questions

What are the CAS number and molecular formula of Azilsartan?

CAS 147403-03-0; molecular formula C25H20N4O5; molecular weight — g/mol.

What other names is Azilsartan known by?

Azilsartan, 147403-03-0, TAK-536, TAK 536, F9NUX55P23, 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid.

Is Azilsartan classified as hazardous?

Hazard statements reported: H360, H361, H362, H372.

What are the key physical properties of Azilsartan?

Melting Point: 212-214 °C; LogP: log Kow = 0.90.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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