✉ info@591daili.com☎ +86-18553102138
📞 WhatsApp中文
591daili 济南圣和化工
Home › Product Catalog › Alfuzosin

Alfuzosin

CAS 81403-80-7C19H27N5O4MW 389.4

Alfuzosin (CAS No. 81403-80-7) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number81403-80-7
Molecular FormulaC19H27N5O4
Molecular Weight389.4
Melting Point240
Boiling Point688
LogP1.604
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Alfuzosin?

The CAS number of Alfuzosin is 81403-80-7.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Alfuzosin?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Alfuzosin or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Alfuzosin · CAS 81403-80-7 · C19H27N5O4. UNII 90347YTW5F. Boiling Point: 688; Melting Point: 240; Solubility: 2.82e-01 g/L.

Identification

CAS Registry Number81403-80-7
PubChem CID2092
Molecular formulaC19H27N5O4
IUPAC nameN-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide
UNII (FDA)90347YTW5F

Computed Descriptors

Molecular Weight389.4
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass389.20630436
Monoisotopic Mass389.20630436
Topological Polar Surface Area112
Heavy Atom Count28
Formal Charge0

Physical & Chemical Properties

Boiling Point688
Melting Point240
Solubility2.82e-01 g/L
LogP1.604
LogP1.4
LogP1.93
Dissociation Constants8.13
Dissociation ConstantspKa = 8.13

Physical description & handling notes

  • Solid
  • In water, 92 mg/L at 25 °C /Estimated/
  • 4.56X10-13 mm Hg at 25 °C /Estimated/
  • log Kow = 1.86 /Estimated/
  • Henry's Law constant = 9.5X10-20 atm-cu m/mol at 25 °C /Estimated/
  • Mol wt: 425.92. Crystals from ethanol + ether, mp 225 °C, also reported earlier as 235 °C (dec). pKa 8.13 /Hydrochloride/

GHS Hazard Classification

Reported hazard statementsH373 (100%)

H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P260, P319, and P501 (click each P-code to see the statement)

Documented Uses

  • Use (kg; approx.) in Germany (2009): >250
  • Consumption (g per capita; approx.) in Germany (2009): 0.00305
  • Preparation: P.M.J. Manoury, DE 2904445; idem, US 4315007 (1979, 1982 both to Synthelabo)
  • Information available in 2004 indicated that Alfuzosin was used in the manufacture of pharmaceutical preparations in the following countries: Argentina, Romania
  • Alfuzosin is used to treat the signs and symptoms of benign prostatic hyperplasia (BPH).
  • Alfuzosin is a nonselective alpha-1 adrenergic antagonist used in the therapy of benign prostatic hypertrophy. Alfuzosin is associated with a low rate of transient serum aminotransferase elevations and with rare instances of clinically apparent acute liver injury.

Synonyms

alfuzosin; 81403-80-7; Alfuzosina; Alfuzosine; Alfuzosinum; NSC-760065; N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide; 90347YTW5F; N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide; DTXSID6048549; CHEBI:51141; alphuzosine; N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide; alfusozine; N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)oxolane-2-carboxamide; N-(3-((4-imino-6,7-dimethoxy-3,4-dihydroquinazolin-2-yl)(methyl)amino)propyl)oxolane-2-carboximidic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Alfuzosin?

CAS 81403-80-7; molecular formula C19H27N5O4; molecular weight — g/mol.

What other names is Alfuzosin known by?

alfuzosin, 81403-80-7, Alfuzosina, Alfuzosine, Alfuzosinum, NSC-760065.

Is Alfuzosin classified as hazardous?

Hazard statements reported: H373.

What are the key physical properties of Alfuzosin?

Boiling Point: 688; Melting Point: 240; Solubility: 2.82e-01 g/L; LogP: 1.604.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

You may also need

Get a quote for Alfuzosin

Supplier: Jinan Shenghe Chemical Co., Ltd. · Reply within one business day.

Email Inquiry WhatsApp
鲁ICP备19031700号-1