Apalutamide

Name: Apalutamide
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 956104-40-8C21H15F4N5O2SMW 477.4

Apalutamide (CAS No. 956104-40-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number956104-40-8

Molecular FormulaC21H15F4N5O2S

Molecular Weight477.4

LogP3

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Apalutamide?

The CAS number of Apalutamide is 956104-40-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Apalutamide?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Apalutamide or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Apalutamide · CAS 956104-40-8 · C21H15F4N5O2S. UNII 4T36H88UA7.

Identification

CAS Registry Number	956104-40-8
PubChem CID	24872560
Molecular formula	C21H15F4N5O2S
IUPAC name	4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide
UNII (FDA)	4T36H88UA7

Computed Descriptors

Molecular Weight	477.4
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	477.08825856
Monoisotopic Mass	477.08825856
Topological Polar Surface Area	121
Heavy Atom Count	33
Formal Charge	0

Physical description & handling notes

practically insoluble in aqueous media

GHS Hazard Classification

Reported hazard statements	H360 (94.6%)

H360 (94.6%): May damage fertility or the unborn child [Danger Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

Documented Uses

Apalutamide is indicated for the treatment of patients with metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer.
Apalutamide is a third generation, oral nonsteroidal antiandrogen used to treat nonmetastatic castration-resistant prostate cancer. Apalutamide is associated with a low rate of serum enzyme elevation during therapy but has not been linked to cases of clinically apparent liver injury with jaundice.
Apalutamide is approved to treat:
• In patients whose cancer has metastasized (spread to other parts of the body) and is castrate sensitive (has responded to treatments that lower testosterone levels).
• In patients whose cancer has not metastasized and is castrate resistant (has not responded to treatments that lower testosterone levels).
Take at the same time every day.

Synonyms

apalutamide; ARN-509; 956104-40-8; Erleada; ARN 509; JNJ-56021927; ARN509; apalutamida; 4T36H88UA7; JNJ 56021927; DTXSID40241899; apalutamidum; RefChem:58966; DTXCID20164390; L02BB05; Apalutamide [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Apalutamide?

CAS 956104-40-8; molecular formula C21H15F4N5O2S; molecular weight — g/mol.

What other names is Apalutamide known by?

apalutamide, ARN-509, 956104-40-8, Erleada, ARN 509, JNJ-56021927.

Is Apalutamide classified as hazardous?

Hazard statements reported: H360.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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