积雪草酸

Description

Asiatic acid · CAS 464-92-6 · C30H48O5. UNII 9PA5A687X5.

Identification

CAS Registry Number	464-92-6
PubChem CID	119034
Molecular formula	C30H48O5
IUPAC name	(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
UNII (FDA)	9PA5A687X5

Computed Descriptors

Molecular Weight	488.7
XLogP3	5.7
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	488.35017463
Monoisotopic Mass	488.35017463
Topological Polar Surface Area	98
Heavy Atom Count	35
Formal Charge	0

Physical description & handling notes

• 233.5 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• The drug "Titrated Extract from Centella asiatica" (TECA), used for its stimulating properties on the healing of wounds, is a mixture of 3 terpenes extracted from a tropical plant: asiatic acid (30%, w/w), madecassic acid (30%, w/w) and asiaticoside (40%, w/w).

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Stabilizing; Skin conditioning
GHS notification summary	99% (104 / 105)

GHS Hazard Classification

GHS notification summary	99% (104 / 105)

Documented Uses

• Cosmetics -> Stabilizing; Skin conditioning
• Isolated from Syzygium claviflorum
• CLASSES: Natural products; triterpenoids
• Titrated extract of Centella asiatica (TECA) contains three principal ingredients, asiaticoside (AS), asiatic acid (AA), and madecassic acid (MA). These components are known to be clinically effective on systemic scleroderma, abnormal scar formation, and keloids. ...
• /EXPL THER/ Asiatic acid, a triterpene of Centella asiatica (L.) Urban (Umbelliferae), has been patented as a treatment for dementia and an enhancer of cognition by the Hoechst Aktiengesellschaft.
• For more Therapeutic Uses (Complete) data for ASIATIC ACID (6 total), please visit the HSDB record page.

Synonyms

Asiatic acid; 464-92-6; Dammarolic acid; 9PA5A687X5; DTXSID901019207; NSC-166063; CHEBI:2873; 2alpha,3beta,23-trihydroxyurs-12-en-28-oic acid; Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2alpha,3beta,4alpha)-; Urs-12en-28-oic acid, 2,3,23-trihydroxy-, (2alpha, 3beta, 4alpha)-; RefChem:28615; DTXCID601477197; 482-720-9; 610-307-7; MFCD00238541; Asiantic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Asiatic acid?

CAS 464-92-6; molecular formula C30H48O5; molecular weight — g/mol.

What other names is Asiatic acid known by?

Asiatic acid, 464-92-6, Dammarolic acid, 9PA5A687X5, DTXSID901019207, NSC-166063.

What is the regulatory status of Asiatic acid?

Documented regulatory listings: CIR / INCI: Stabilizing; Skin conditioning.

Is Asiatic acid classified as hazardous?

99% of GHS notifications report no hazard classification (104 of 105).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.