阿巴洛帕拉肽

Description

abaloparatide · CAS 247062-33-5 · C174H300N56O49. UNII AVK0I6HY2U.

Identification

CAS Registry Number	247062-33-5
PubChem CID	76943386
Molecular formula	C174H300N56O49
UNII (FDA)	AVK0I6HY2U

Computed Descriptors

Molecular Weight	3961
XLogP3	-20.9
Hydrogen Bond Donor Count	61
Hydrogen Bond Acceptor Count	60
Rotatable Bond Count	145
Exact Mass	3959.2738250
Monoisotopic Mass	3958.2704702
Topological Polar Surface Area	1740
Heavy Atom Count	279
Formal Charge	0

Physical description & handling notes

• Soluble

Documented Uses

• Abaloparatide, a synthetic peptide analog of parathyroid hormone-related protein (PTHrP), is used to manage and treat osteoporosis. Osteoporosis is characterized by reduced bone mineral density (BMD) due to changes in bone microstructure, resulting in an elevated risk of fractures. BMD is commonly measured utilizing a dual-energy x-ray absorptiometry (DEXA or DXA) scan to assess BMD.
• Administer vitamin supplements. If dietary intake is inadequate, patients should receive supplemental calcium and vitamin D.
• Take at the same time every day.
• Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.
• Established Pharmacologic Class [EPC] - Parathyroid Hormone-Related Peptide Analog
• Chemical Structure [CS] - Parathyroid Hormone-Related Protein

Synonyms

Abaloparatide; Tymlos; BA058; 247062-33-5; BIM-44058; AVK0I6HY2U; abaloparatida; abaloparatidum; RefChem:58773; DTXSID201027906; BA-058; UNII-AVK0I6HY2U; Abaloparatide [USAN:INN]; Abaloparatide-SC; CHEMBL4084894; SCHEMBL29379965

Frequently Asked Questions

What are the CAS number and molecular formula of abaloparatide?

CAS 247062-33-5; molecular formula C174H300N56O49; molecular weight — g/mol.

What other names is abaloparatide known by?

Abaloparatide, Tymlos, BA058, 247062-33-5, BIM-44058, AVK0I6HY2U.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.