倍他米松17,21-二丙酸酯

Description

Betamethasone Dipropionate · CAS 5593-20-4 · C28H37FO7. UNII 826Y60901U. LogP: 4.07.

Identification

CAS Registry Number	5593-20-4
PubChem CID	21800
Molecular formula	C28H37FO7
IUPAC name	[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
UNII (FDA)	826Y60901U

Computed Descriptors

Molecular Weight	504.6
XLogP3	3.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	8
Exact Mass	504.25233168
Monoisotopic Mass	504.25233168
Topological Polar Surface Area	107
Heavy Atom Count	36
Formal Charge	0

Physical & Chemical Properties

LogP	4.07

Physical description & handling notes

• 218.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	1.6% (2 / 127)

GHS Hazard Classification

GHS notification summary	1.6% (2 / 127)
Reported hazard statements	H330 (40.9%), H360 (37.8%), H361 (45.7%), H372 (50.4%), H410 (50.4%)

Documented Uses

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Substances that reduce or suppress INFLAMMATION.
• A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
• Corticosteroid [EPC]; Corticosteroid Hormone Receptor Agonists [MoA]
• BETAMETHASONE DIPROPIONATE USP, 0.05%
• Corticosteroid Hormone Receptor Agonists [MoA]; Corticosteroid [EPC]

Synonyms

BETAMETHASONE DIPROPIONATE; 5593-20-4; Diprosone; Diprolene; Alphatrex; Maxivate; Betamethasone 17,21-dipropionate; Rinderon DP; Diprolene AF; Diprospan; Sch 11460; Sernivo; Sch-11460; DTXSID2022672; beta-Methasone 17,21-dipropionate; Betamethasone (as dipropionate)

Frequently Asked Questions

What are the CAS number and molecular formula of Betamethasone Dipropionate?

CAS 5593-20-4; molecular formula C28H37FO7; molecular weight — g/mol.

What other names is Betamethasone Dipropionate known by?

BETAMETHASONE DIPROPIONATE, 5593-20-4, Diprosone, Diprolene, Alphatrex, Maxivate.

Is Betamethasone Dipropionate classified as hazardous?

1.6% of GHS notifications report no hazard classification (2 of 127).

What are the key physical properties of Betamethasone Dipropionate?

LogP: 4.07.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.