次没食子酸铋

Description

BISMUTH SUBGALLATE · CAS 22650-86-8 · C7H5BiO6. UNII YIW503MI7V. European Pharmacopoeia monograph.

Identification

CAS Registry Number	22650-86-8
PubChem CID	73415769
Molecular formula	C7H5BiO6
IUPAC name	bismuth;5-carboxy-3-hydroxybenzene-1,2-diolate;hydroxide
UNII (FDA)	YIW503MI7V
Pharmacopoeial monograph	European Pharmacopoeia monograph

Computed Descriptors

Molecular Weight	394.09
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	1
Exact Mass	393.98901
Monoisotopic Mass	393.98901
Topological Polar Surface Area	105
Heavy Atom Count	14
Formal Charge	0
Complexity	181

Physical description & handling notes

• Insoluble in cold water and hot water.

Regulatory Status

GHS notification summary	96.7% (29 / 30)

GHS Hazard Classification

GHS notification summary	96.7% (29 / 30)

Documented Uses

• 1,3,2-Benzodioxabismole-5-carboxylic acid, 2,7-dihydroxy-: ACTIVE
• Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
• Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.
• Ingested bismuth is primarily eliminated unabsorbed by way of the faeces. Any absorbed bismuth is eliminated from the body by both the urinary and faecal (including bile) routes. Excretion of absorbed bismuth in the urine is rapid, with most of the metal excreted within 24 hours. About 10% of the absorbed bismuth is detected in faeces, presumably owing to biliary secretion.
• In general, oral administration is one of the most common routes of administration for non-prescription bismuth subgallate products and gastrointestinal and systemic absorption is usually very low.
• On average, the blood clearance of the bismuth component of a bismuth salt like bismuth subgallate is within the range of 50 to 95 ml/min.

Synonyms

Devrom; RefChem:57653; 607-121-3; 1,3,2-Benzodioxabismole-5-carboxylic acid, 2,7-dihydroxy-; 2,7-dihydroxy-2H-benzo(d)1,3-dioxa-2-bismacyclopentane-5-carboxylic acid; 99-26-3; basic bismuth 3,4,5-trihydroxybenzoate; Basic bismuth gallate; Bismuth Subgallate; CHEBI:31292; Dermatol; DTXCID1026588; DTXSID3046588; Gallic acid bismuth basic salt; Wismutgallathydroxid; YIW503MI7V

Frequently Asked Questions

What are the CAS number and molecular formula of BISMUTH SUBGALLATE?

CAS 22650-86-8; molecular formula C7H5BiO6; molecular weight — g/mol.

What other names is BISMUTH SUBGALLATE known by?

Devrom, RefChem:57653, 607-121-3, 1,3,2-Benzodioxabismole-5-carboxylic acid, 2,7-dihydroxy-, 2,7-dihydroxy-2H-benzo(d)1,3-dioxa-2-bismacyclopentane-5-carboxylic acid, 99-26-3.

Is BISMUTH SUBGALLATE classified as hazardous?

96.7% of GHS notifications report no hazard classification (29 of 30).

Does BISMUTH SUBGALLATE have a pharmacopoeial monograph?

Yes — a monograph exists in the European Pharmacopoeia (Ph. Eur.).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.