贝尼地平

Description

Benidipine · CAS 105979-17-7 · C28H31N3O6. UNII 4G9T91JS7E. Melting Point: >193ºC; Solubility: <1 mg/ml; LogP: 3.79.

Identification

CAS Registry Number	105979-17-7
PubChem CID	656668
Molecular formula	C28H31N3O6
IUPAC name	5-O-[(3R)-1-benzylpiperidin-3-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
UNII (FDA)	4G9T91JS7E

Computed Descriptors

Molecular Weight	505.6
XLogP3	4.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	8
Exact Mass	505.22128572
Monoisotopic Mass	505.22128572
Topological Polar Surface Area	114
Heavy Atom Count	37
Formal Charge	0

Physical & Chemical Properties

Melting Point	>193ºC
Solubility	<1 mg/ml
LogP	3.79
LogP	3.47
Dissociation Constants	7.34

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Benidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris.
• A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
• Drugs used to cause dilation of the blood vessels.
• C08C - Selective calcium channel blockers with mainly vascular effects
• C08CA - Dihydropyridine derivatives
• QC08 - Calcium channel blockers

Synonyms

Benidipine; 105979-17-7; Benidipinum; Benidipino; 4G9T91JS7E; RefChem:561249; C08CA15; Benidipene; 119065-60-0; Benidipine [INN]; Benidipine (INN); Benidipinum [Latin]; Benidipino [Spanish]; (-)-Alpha Benidipine; NCGC00185768-01; UNII-4G9T91JS7E

Frequently Asked Questions

What are the CAS number and molecular formula of Benidipine?

CAS 105979-17-7; molecular formula C28H31N3O6; molecular weight — g/mol.

What other names is Benidipine known by?

Benidipine, 105979-17-7, Benidipinum, Benidipino, 4G9T91JS7E, RefChem:561249.

Is Benidipine classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of Benidipine?

Melting Point: >193ºC; Solubility: <1 mg/ml; LogP: 3.79; LogP: 3.47.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.