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Brigatinib

CAS 1197953-54-0C29H39ClN7O2PMW 584.1

Brigatinib (CAS No. 1197953-54-0) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1197953-54-0
Molecular FormulaC29H39ClN7O2P
Molecular Weight584.1
LogP5.17
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Brigatinib?

The CAS number of Brigatinib is 1197953-54-0.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Brigatinib?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Brigatinib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Brigatinib · CAS 1197953-54-0 · C29H39ClN7O2P. UNII HYW8DB273J. LogP: 5.17.

Identification

CAS Registry Number1197953-54-0
PubChem CID68165256
Molecular formulaC29H39ClN7O2P
IUPAC name5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine
UNII (FDA)HYW8DB273J

Computed Descriptors

Molecular Weight584.1
XLogP34.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count8
Exact Mass583.2591382
Monoisotopic Mass583.2591382
Topological Polar Surface Area85.9
Heavy Atom Count40
Formal Charge0

Physical & Chemical Properties

LogP5.17

Physical description & handling notes

  • Insoluble

GHS Hazard Classification

Reported hazard statementsH301 (100%), H361 (100%), H372 (100%), H410 (100%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Brigatinib is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer. Brigatinib is associated with a moderate rate of transient elevations in serum aminotransferase levels during therapy but has yet to be linked to instances of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Tyrosine Kinase Inhibitors;
  • Brigatinib is approved to treat:
  • • Non-small cell lung cancer that is ALK positive and has metastasized (spread to other parts of the body). It is used in adults.
  • Brigatinib is also being studied in the treatment of other types of cancer.
  • Avoid grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of brigatinib.

Synonyms

Brigatinib; 1197953-54-0; ALUNBRIG; AP-26113; HYW8DB273J; DTXSID501027929; brigatinibum; RefChem:56949; L01XE43; DTXCID501513495; AP 26113; Brigatinib [USAN]; Brigatinib (AP-26113); MFCD29472221; Brigatinib (AP26113); NCGC00483924-01

Frequently Asked Questions

What are the CAS number and molecular formula of Brigatinib?

CAS 1197953-54-0; molecular formula C29H39ClN7O2P; molecular weight — g/mol.

What other names is Brigatinib known by?

Brigatinib, 1197953-54-0, ALUNBRIG, AP-26113, HYW8DB273J, DTXSID501027929.

Is Brigatinib classified as hazardous?

Hazard statements reported: H301, H361, H372, H410.

What are the key physical properties of Brigatinib?

LogP: 5.17.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd. · Reply within one business day.

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