硫酸小檗碱

Description

berberine sulphate · CAS 316-41-6 · C40H36N2O12S. UNII FST3E667FF.

Identification

CAS Registry Number	316-41-6
PubChem CID	9424
Molecular formula	C40H36N2O12S
IUPAC name	bis(16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene);sulfate
UNII (FDA)	FST3E667FF

Computed Descriptors

Molecular Weight	768.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	4
Exact Mass	768.19889576
Monoisotopic Mass	768.19889576
Topological Polar Surface Area	170
Heavy Atom Count	55
Formal Charge	0
Complexity	551

Physical description & handling notes

• YELLOW CRYSTALS
• INSOL IN CHLOROFORM /TRIHYDRATE/
• DISASTER HAZARD: DANGEROUS; WHEN HEATED TO DECOMPOSITION, EMITS HIGHLY TOXIC FUMES. /BERBERINE/
• RED-YELLOW NEEDLES /TRIHYDRATE/
• YELLOW NEEDLES /TRIHYDRATE/
• SOLUBLE IN ABOUT 30 PARTS WATER, IN ALC /TRIHYDRATE/

GHS Hazard Classification

Reported hazard statements	H301 (100%), H311 (100%), H331 (100%)

Documented Uses

• /BERBERINE IS/ ALKALOID, USUALLY AS SULFATE; OBTAINED FROM RHIZOMES AND ROOTS OF HYDRASTIS CANADENSIS.
• /BERBERINE/...BEHAVES AS A QUATERNARY BASE, FORMING SALTS BY REPLACEMENT OF THE OH GROUP: PERKIN, JR, J CHEM SOC 113, 503 (1918). /BERBERINE/
• EXPTL USE (VET): ORALLY ADMIN BERBERINE SULFATE (350-700 MG/KG) WAS EFFECTIVE IN TREATING CANDIDA ALBICANS INFECTIONS OF THE INTESTINE IN MICE.
• EXPTL USE: DILATION OF HUMAN EYE PUPILS, TOPICAL ANESTHESIA &/OR FLUORESCENT STAINING OF CORNEAL EPITHELIAL DEFECTS &/OR FLUORESCENCE IN APPLANATION TONOMETRY, IS ACCOMPLISHED BY TOPICAL APPLICATION OF OPHTHALMIC SOLN OF HYDRASTIS COMPD SUCH AS BERBERINE.
• /PRC: FORMER USES/ BITTER STOMACHIC; ANTIBACTERIAL; ANTIMALARIAL; ANTIPYRETIC /BERBERINE/
• MILD LOCAL ANESTHETIC ON MUCOUS MEMBRANE. /BERBERINE/

Synonyms

Berberine sulphate; Berberin sulfate; Berberine sulfate (2:1); Neutral berberine sulfate; Erben; Berberine sulfate anhydrous; FST3E667FF; Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate (2:1); Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydr0-9,10-dimethoxy-, sulfate (2:1); Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, sulfate (2:1); NSC-5355; RefChem:1079543; 206-258-2; Berberine sulfate; 6190-33-6; Berberal

Frequently Asked Questions

What are the CAS number and molecular formula of berberine sulphate?

CAS 316-41-6; molecular formula C40H36N2O12S; molecular weight — g/mol.

What other names is berberine sulphate known by?

Berberine sulphate, Berberin sulfate, Berberine sulfate (2:1), Neutral berberine sulfate, Erben, Berberine sulfate anhydrous.

Is berberine sulphate classified as hazardous?

Hazard statements reported: H301, H311, H331.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.