比克替拉韦

Name: 比克替拉韦
Brand: 济南圣和化工有限公司

CAS 1611493-60-7C21H18F3N3O5MW 449.4

比克替拉韦，CAS 登记号 1611493-60-7，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号1611493-60-7

分子式C21H18F3N3O5

分子量449.4

沸点682.5±55.0 °C at 760 mmHg

LogP2.7

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

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本页已列出比克替拉韦的 CAS 号：1611493-60-7，可与随货 COA 核对。

可以提供哪些规格和包装？

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比克替拉韦一般用在什么产品里？

主要涉及医药中间体及原料药。

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PubChem 公开数据

Description

Bictegravir · CAS 1611493-60-7 · C21H18F3N3O5. UNII 8GB79LOJ07. Boiling Point: 682.5±55.0 °C at 760 mmHg.

Identification

CAS Registry Number	1611493-60-7
PubChem CID	90311989
Molecular formula	C21H18F3N3O5
IUPAC name	(1S,11R,13R)-5-hydroxy-3,6-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-12-oxa-2,9-diazatetracyclo[11.2.1.02,11.04,9]hexadeca-4,7-diene-7-carboxamide
UNII (FDA)	8GB79LOJ07

Computed Descriptors

Molecular Weight	449.4
XLogP3	2.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	449.11985517
Monoisotopic Mass	449.11985517
Topological Polar Surface Area	99.2
Heavy Atom Count	32
Formal Charge	0

Physical & Chemical Properties

Boiling Point	682.5±55.0 °C at 760 mmHg

Physical description & handling notes

Bictegravir is an HIV-1 integrase strand transfer inhibitor (INSTI). Bictegravir (BIC) inhibits HIV-1 virus replication into the human genome. It can be taken once daily without additional dosing. Bictegravir (BIC) inhibits strand transfer of viral DNA into the host genome and thereby prevents HIV-1 replication.

Documented Uses

Bictegravir is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor, the fourth in this class of agents that target the viral integrase. Bictegravir is used only in combination with other antiretroviral agents in the treatment of HIV infection and it has had limited use. Bictegravir is associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of acute, clinically apparent liver injury.
Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; HIV Integrase Inhibitors
Take at the same time every day.
Take separate from antacids. Take bictegravir at least 2 hours before or 6 hours after taking antacids containing aluminum or magnesium.
Take with food. When taking iron or calcium-containing products, bictegravir should be taken with food.
Bictegravir is rapidly absorbed within the body. Tmax= 2.0-4.0h

Synonyms

Bictegravir; 1611493-60-7; GS-9883; bictegravirum; GS-9883-01; 8GB79LOJ07; CHEBI:172943; DTXSID701027937; RefChem:568041; DTXCID901513504; Bictegravir [INN]; GS 9883; BICTEGRAVIR [USAN]; BICTEGRAVIR [WHO-DD]; D10909; Bictegravir (100 mg/mL in DMSO)

Frequently Asked Questions

What are the CAS number and molecular formula of Bictegravir?

CAS 1611493-60-7; molecular formula C21H18F3N3O5; molecular weight — g/mol.

What other names is Bictegravir known by?

Bictegravir, 1611493-60-7, GS-9883, bictegravirum, GS-9883-01, 8GB79LOJ07.

What are the key physical properties of Bictegravir?

Boiling Point: 682.5±55.0 °C at 760 mmHg.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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