贝凡洛尔

Description

Bevantolol · CAS 59170-23-9 · C20H27NO4. UNII 34ZXW6ZV21. Melting Point: 137-138 °C; Melting Point: 137 - 138 °C; Solubility: 1.37e-02 g/L.

Identification

CAS Registry Number	59170-23-9
PubChem CID	2372
Molecular formula	C20H27NO4
IUPAC name	1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol
UNII (FDA)	34ZXW6ZV21

Computed Descriptors

Molecular Weight	345.4
XLogP3	3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	345.19400834
Monoisotopic Mass	345.19400834
Topological Polar Surface Area	60
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	137-138 °C
Melting Point	137 - 138 °C
Solubility	1.37e-02 g/L
LogP	3.00
LogP	3.0

Physical description & handling notes

• Solid
• Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.

Documented Uses

• For the treatment of angina pectoris and hypertension.
• Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS.
• C07AB - Beta blocking agents, selective
• QC07AB - Beta blocking agents, selective
• Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors. By binding and antagonizing beta-1 receptors Bevantolol inhibits the normal normal epinephrine-mediated sympathetic actions such as increased heart rate. This has the effect of decreasing preload and blood pressure.

Synonyms

Bevantolol; 59170-23-9; Bevantololum; 1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; (+-)-bevantolol; 1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol; NSC-132348; 34ZXW6ZV21; 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol; 1-(3,4-dimethoxyphenethylamino)-3-m-tolyloxy-propan-2-ol; CHEBI:238698; DTXSID70860597; 1-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-ol; CI-775; 1-(2-(3,4-Dimethoxy-phenyl)-ethylamino)-3-m-tolyloxy-propan-2-ol; 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)propan-2-ol

Frequently Asked Questions

What are the CAS number and molecular formula of Bevantolol?

CAS 59170-23-9; molecular formula C20H27NO4; molecular weight — g/mol.

What other names is Bevantolol known by?

Bevantolol, 59170-23-9, Bevantololum, 1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol, (+-)-bevantolol, 1-((2-(3,4-Dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol.

What are the key physical properties of Bevantolol?

Melting Point: 137-138 °C; Melting Point: 137 - 138 °C; Solubility: 1.37e-02 g/L; LogP: 3.00.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.