双(4-氯苯基)乙酸

Description

bis(4-chlorophenyl)acetic acid · CAS 83-05-6 · C14H10Cl2O2. UNII N0U8S29G6E. LogP: 4.64.

Identification

CAS Registry Number	83-05-6
PubChem CID	6730
Molecular formula	C14H10Cl2O2
IUPAC name	2,2-bis(4-chlorophenyl)acetic acid
UNII (FDA)	N0U8S29G6E

Computed Descriptors

Molecular Weight	281.1
XLogP3	4.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	280.0057849
Monoisotopic Mass	280.0057849
Topological Polar Surface Area	37.3
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

LogP	4.64

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (97.5%), H332 (97.5%), H351 (100%)

Documented Uses

• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
• Substances that stimulate mitosis and lymphocyte transformation. They include not only substances associated with LECTINS, but also substances from streptococci (associated with streptolysin S) and from strains of alpha-toxin-producing staphylococci. (Stedman, 25th ed)

Synonyms

Bis(4-chlorophenyl)acetic acid; 2,2-Bis(4-chlorophenyl)acetic acid; 83-05-6; BIS(P-CHLOROPHENYL)ACETIC ACID; Dichlorodiphenylacetic acid; 2,2-Bis(p-chlorophenyl)acetic acid; p,p'-Dichlorodiphenylacetic acid; Di(p-chlorophenyl)acetic acid; Bis(p-chlorphenyl)essigsaeure; Acetic acid, bis(p-chlorophenyl)-; N0U8S29G6E; 4-Chloro-alpha-(4-chlorophenyl)benzeneacetic acid; CHEBI:28139; Benzeneacetic acid, 4-chloro-alpha-(4-chlorophenyl)-; NSC-4279; RefChem:120141

Frequently Asked Questions

What are the CAS number and molecular formula of bis(4-chlorophenyl)acetic acid?

CAS 83-05-6; molecular formula C14H10Cl2O2; molecular weight — g/mol.

What other names is bis(4-chlorophenyl)acetic acid known by?

Bis(4-chlorophenyl)acetic acid, 2,2-Bis(4-chlorophenyl)acetic acid, 83-05-6, BIS(P-CHLOROPHENYL)ACETIC ACID, Dichlorodiphenylacetic acid, 2,2-Bis(p-chlorophenyl)acetic acid.

Is bis(4-chlorophenyl)acetic acid classified as hazardous?

Hazard statements reported: H302, H312, H332, H351.

What are the key physical properties of bis(4-chlorophenyl)acetic acid?

LogP: 4.64.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.