二盐酸氯己定

Description

Chlorhexidine HCL · CAS 3697-42-5 · C22H30Cl2N10.2ClH. UNII E64XL9U38K.

Identification

CAS Registry Number	3697-42-5
PubChem CID	9571016
Molecular formula	C22H30Cl2N10.2ClH
IUPAC name	(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;dihydrochloride
UNII (FDA)	E64XL9U38K

Computed Descriptors

Molecular Weight	578.4
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	13
Exact Mass	578.153602
Monoisotopic Mass	576.156552
Topological Polar Surface Area	178
Heavy Atom Count	36
Formal Charge	0
Complexity	648

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Chlorhexidine Dihydrochloride) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Preservative
GHS notification summary	0.9% (1 / 115)

GHS Hazard Classification

GHS notification summary	0.9% (1 / 115)
Reported hazard statements	H315 (60.9%), H319 (98.3%), H335 (60%), H373 (11.3%), H400 (16.5%), H410 (15.7%), H411 (22.6%), H317

Documented Uses

• CIR ingredient: Chlorhexidine Dihydrochloride
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Information on 68 consumer products that contain Chlorhexidine dihydrochloride in the following categories is provided:
• Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
• Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
• Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)

Synonyms

CHLORHEXIDINE HYDROCHLORIDE; Chlorhexidine dihydrochloride; 3697-42-5; Chlorhexidine HCl; Dantroche hibitane; AY-5312; DTXSID7047144; E64XL9U38K; NSC-756679; 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, dihydrochloride; DTXCID5027144; Chlorhex hcl; 1,1'-Hexamethylenebis(5-(4-chlorophenyl)biguanide) dihydrochloride; 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Dihydrochloride; Nolvasan Cap-Tabs; Nolvasan Suspension

Frequently Asked Questions

What are the CAS number and molecular formula of Chlorhexidine HCL?

CAS 3697-42-5; molecular formula C22H30Cl2N10.2ClH; molecular weight — g/mol.

What other names is Chlorhexidine HCL known by?

CHLORHEXIDINE HYDROCHLORIDE, Chlorhexidine dihydrochloride, 3697-42-5, Chlorhexidine HCl, Dantroche hibitane, AY-5312.

What is the regulatory status of Chlorhexidine HCL?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Chlorhexidine Dihydrochloride) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Preservative.

Is Chlorhexidine HCL classified as hazardous?

0.9% of GHS notifications report no hazard classification (1 of 115).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.