盐酸氯米帕明

Description

clomipramine hydrochloride · CAS 17321-77-6 · C19H24Cl2N2. UNII 2LXW0L6GWJ.

Identification

CAS Registry Number	17321-77-6
PubChem CID	68539
Molecular formula	C19H24Cl2N2
IUPAC name	3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride
UNII (FDA)	2LXW0L6GWJ

Computed Descriptors

Molecular Weight	351.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	350.1316542
Monoisotopic Mass	350.1316542
Topological Polar Surface Area	6.5
Heavy Atom Count	23
Formal Charge	0
Complexity	346

Physical description & handling notes

• 173.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (65.6%), H315 (63.9%), H319 (63.9%), H332 (65.6%), H335 (62.3%), H361 (24.6%), H400 (26.2%)

Documented Uses

• May be used to treat obsessive-compulsive disorder and disorders with an obsessive-compulsive component (e.g. depression, schizophrenia, Tourette's disorder). Unlabeled indications include: depression, panic disorder, chronic pain (e.g. central pain, idiopathic pain disorder, tension headache, diabetic peripheral neuropathy, neuropathic pain), cataplexy and associated narcolepsy (limited evidence), autistic disorder (limited evidence), trichotillomania (limited evidence), onchophagia (limited evidence), stuttering
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• Compounds that specifically inhibit the reuptake of serotonin in the brain.
• CLOMIPRAMINE HYDROCHLORIDE CAPSULES

Synonyms

Clomipramine hydrochloride; 17321-77-6; Clomipramine HCL; 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride; 3-Chloroimipramine hydrochloride; Chloroimipramine monohydrochloride; DTXSID3042633; 2LXW0L6GWJ; NSC-759323; G 34586; G-34586; 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride; 5H-Dibenz(b,f)azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride; CHEBI:3755; DTXCID1022633; 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine monohydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of clomipramine hydrochloride?

CAS 17321-77-6; molecular formula C19H24Cl2N2; molecular weight — g/mol.

What other names is clomipramine hydrochloride known by?

Clomipramine hydrochloride, 17321-77-6, Clomipramine HCL, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride, 3-Chloroimipramine hydrochloride, Chloroimipramine monohydrochloride.

Is clomipramine hydrochloride classified as hazardous?

Hazard statements reported: H302, H312, H315, H319, H332.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.