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Cilazapril

CAS 88768-40-5C22H31N3O5MW 417.5

Cilazapril (CAS No. 88768-40-5) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number88768-40-5
Molecular FormulaC22H31N3O5
Molecular Weight417.5
Melting Point98
LogP0.8
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Cilazapril?

The CAS number of Cilazapril is 88768-40-5.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Cilazapril?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Cilazapril or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Cilazapril · CAS 88768-40-5 · C22H31N3O5. UNII 8Q9454114Q. Melting Point: 98; Solubility: 1.06e+00 g/L; LogP: 0.8.

Identification

CAS Registry Number88768-40-5
PubChem CID56330
Molecular formulaC22H31N3O5
IUPAC name(4S,7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid
UNII (FDA)8Q9454114Q

Computed Descriptors

Molecular Weight417.5
XLogP30.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass417.22637110
Monoisotopic Mass417.22637110
Topological Polar Surface Area99.2
Heavy Atom Count30
Formal Charge0

Physical & Chemical Properties

Melting Point98
Solubility1.06e+00 g/L
LogP0.8
LogP0.55

Physical description & handling notes

  • Solid
  • Water (25 ºC) 0.5 g/100 mL

Documented Uses

  • Use (kg; approx.) in Germany (2009): >10
  • Consumption (g per capita; approx.) in Germany (2009): 0.000122
  • Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure.
  • Take with or without food. Food decreases absorption, but not to a clinically significant extent.
  • A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
  • Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Synonyms

cilazapril; 88768-40-5; Inhibace; Cilazapril anhydrous; Cilazaprilum; Vascace; Justor; Anhydrous cilazapril; Ro 34-2848; Initiss; DTXSID1048629; Ro-312848006; CHEBI:3698; 8Q9454114Q; DTXCID8028555; RO-31-2848/006

Frequently Asked Questions

What are the CAS number and molecular formula of Cilazapril?

CAS 88768-40-5; molecular formula C22H31N3O5; molecular weight — g/mol.

What other names is Cilazapril known by?

cilazapril, 88768-40-5, Inhibace, Cilazapril anhydrous, Cilazaprilum, Vascace.

What are the key physical properties of Cilazapril?

Melting Point: 98; Solubility: 1.06e+00 g/L; LogP: 0.8; LogP: 0.55.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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