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Clobetasol

CAS 25122-41-2C22H28ClFO4MW 410.9

Clobetasol (CAS No. 25122-41-2) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number25122-41-2
Molecular FormulaC22H28ClFO4
Molecular Weight410.9
Melting Point195.5 - 197 °C
LogPlog Kow = 2.48
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Clobetasol?

The CAS number of Clobetasol is 25122-41-2.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Clobetasol?

Main applications include Organic Chemicals.

How do I buy Clobetasol or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Clobetasol · CAS 25122-41-2 · C22H28ClFO4. UNII ADN79D536H. Melting Point: 195.5 - 197 °C; Solubility: 1.42e-02 g/L; LogP: log Kow = 2.48.

Identification

CAS Registry Number25122-41-2
PubChem CID5311051
Molecular formulaC22H28ClFO4
IUPAC name(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
UNII (FDA)ADN79D536H

Computed Descriptors

Molecular Weight410.9
XLogP32.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass410.1660152
Monoisotopic Mass410.1660152
Topological Polar Surface Area74.6
Heavy Atom Count28
Formal Charge0

Physical & Chemical Properties

Melting Point195.5 - 197 °C
Solubility1.42e-02 g/L
LogPlog Kow = 2.48
LogP2.48

Physical description & handling notes

  • Solid
  • 201.29 Ų [M+H]+ [CCS Type: TW]
  • White to cream-colored crystalline powder /Clobetasol propionate/
  • White or or almost white colorless, crystalline powder, mp: 195.5-197 °C. Specific optical rotation: +103.8 deg at 25 °C/D (c = 1.04 in dioxane). UV max (ethanol): 237 nm (epsilon = 15000). Insoluble in water. /Clobetasol 17-propionate/
  • Table: Clobetasol Propionate Preparations [Table#7933]

GHS Hazard Classification

Reported hazard statementsH360 (94.8%), H373 (98.3%), H413 (94.8%)

H360 (94.8%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H373 (98.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Documented Uses

  • Use (kg; approx.) in Germany (2009): >10
  • Consumption (g per capita; approx.) in Germany (2009): 0.000122
  • Consumption (g per capita) in the USA (2002): 0.000177
  • Preparation: Elks et al., DE 1902340; eidem, US 3721687 (1969, 1973 both to Glaxo)
  • Breast Feeding; Lactation; Corticosteroids, Topical; Glucocorticoids; Anti-Inflammatory Agents
  • Anti-Inflammatory Agents; Glucocorticoids

Synonyms

clobetasol; 25122-41-2; Clobetasolum; DTXSID2048955; Clobecort Amex; 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione; ADN79D536H; (11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; DTXCID9028881; CHEBI:205919; Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11beta,16beta)-; clobetasolo; Clofenazon; RefChem:54853; D07AD01; 246-633-8

Frequently Asked Questions

What are the CAS number and molecular formula of Clobetasol?

CAS 25122-41-2; molecular formula C22H28ClFO4; molecular weight — g/mol.

What other names is Clobetasol known by?

clobetasol, 25122-41-2, Clobetasolum, DTXSID2048955, Clobecort Amex, 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione.

Is Clobetasol classified as hazardous?

Hazard statements reported: H360, H373, H413.

What are the key physical properties of Clobetasol?

Melting Point: 195.5 - 197 °C; Solubility: 1.42e-02 g/L; LogP: log Kow = 2.48; LogP: 2.48.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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