氯硫平

Description

clotiapine · CAS 2058-52-8 · C18H18ClN3S. UNII Z05HCY0X1T.

Identification

CAS Registry Number	2058-52-8
PubChem CID	16351
Molecular formula	C18H18ClN3S
IUPAC name	8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzothiazepine
UNII (FDA)	Z05HCY0X1T

Computed Descriptors

Molecular Weight	343.9
XLogP3	3.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	343.0909965
Monoisotopic Mass	343.0909965
Topological Polar Surface Area	44.1
Heavy Atom Count	23
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H301 (75%), H302 (25%), H332 (25%), H400 (100%), H410 (100%)

Documented Uses

• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• N05AH - Diazepines, oxazepines, thiazepines and oxepines
• QN05AH - Diazepines, oxazepines, thiazepines and oxepines

Synonyms

Clothiapine; Clotiapine; 2058-52-8; Entumin; Clotiapina; Clotiapinum; DTXSID5022851; HF-2159; DIBENZO(b,f)(1,4)THIAZEPINE, 2-CHLORO-11-(4-METHYL-1-PIPERAZINYL)-; Dibenzo[b,f][1,4]thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-; Z05HCY0X1T; 2-Chloro-11-(4-methyl-1-piperazinyl)dibenzo(b,f)(1,4)thiazepine; DTXCID702851; 2-chloro-11-(4-methyl-1-piperazinyl)dibenzo[b,f][1,4]thiazepine; RefChem:127122; N05AH06

Frequently Asked Questions

What are the CAS number and molecular formula of clotiapine?

CAS 2058-52-8; molecular formula C18H18ClN3S; molecular weight — g/mol.

What other names is clotiapine known by?

Clothiapine, Clotiapine, 2058-52-8, Entumin, Clotiapina, Clotiapinum.

Is clotiapine classified as hazardous?

Hazard statements reported: H301, H302, H332, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.