乙二胺四乙酸二钠钙二水合物

Description

Calcium disodium edetate dihydrate · CAS 23411-34-9 · C10H12CaN2O8.2Na. UNII 8U5D034955. Melting Point: >300; Color Additive Status: 73.1; Color Additive Status: 172.120.

Identification

CAS Registry Number	23411-34-9
PubChem CID	6093170
Molecular formula	C10H12CaN2O8.2Na
IUPAC name	calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
UNII (FDA)	8U5D034955

Computed Descriptors

Molecular Weight	374.27
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	7
Exact Mass	374.0014948
Monoisotopic Mass	374.0014948
Topological Polar Surface Area	167
Heavy Atom Count	23
Formal Charge	0
Complexity	293

Physical & Chemical Properties

Melting Point	>300
Color Additive Status	73.1
Color Additive Status	172.120
Color Additive Status	172.135
Color Additive Status	175.105

Physical description & handling notes

• CBI; Other Solid; Dry Powder; Liquid
• White, odourless crystalline granules or white to nearly white powder, slightly hygroscopic
• White odorless solid; Slightly hygroscopic; [HSDB]
• Powder
• White powder or flakes
• Odorless

Regulatory Status

Regulatory & Food Contact	FDA Regulatory Status of Color Additives: Foods, Drugs FDA Substance added to food: ANTIOXIDANT, COLOR OR COLORING ADJUNCT, FLAVOR ENHANCER, FUMIGANT, SEQUESTRANT FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS PRESERVATIVE; SEQUESTRANT: Food Additives EDTA, CALCIUM DISODIUM Calcium disodium ethylenediaminetetraacetate (EDTA)
GHS notification summary	81.1% (210 / 259)

GHS Hazard Classification

GHS notification summary	81.1% (210 / 259)
Reported hazard statements	H315 (17.4%), H319 (17.4%), H335 (17.4%)

Documented Uses

• CIR ingredient: Calcium Disodium EDTA
• Used as an antidote in metal poisoning, a sequestering agent in foods, an in vitro anticoagulant of blood, and an antigushing agent in beer; Also used in drugs, cosmetics, and other chemicals to sequester trace minerals and prevent oxidation and discoloration; [HSDB]
• Used in pharmaceutical formulations as a chelating agent in concentrations between 0.01-0.1% w/v. Usually edentate calcium disodium is used in pharmaceutical formulations in preference to edentate or sodium edentate to prevent calcium depletion occurring in the body.
• Calcium Disodium EDTA is a preservative, sequestrant, flavoring agent, and color retention agent.
• ... Antigushing agent in fermented malt beverages.
• Food Additives -> PRESERVATIVE; SEQUESTRANT -> JECFA Functional Classes

Synonyms

Edetate calcium disodium; EDTA calcium disodium; Detoxamin; Calcium disodium ethylenediaminetetraacetate; Edetate calcium disodium anhydrous; DTXSID2036409; INS NO.385; INS-385; Edetate Calcium Disodium (anhydrous); NSC-310151; C10H12CaN2Na2O8; DTXCID0016409; E-385; 8U5D034955; Calcium disodium edetate hydrate; Calcium disodium EDTA dihydrate

Frequently Asked Questions

What are the CAS number and molecular formula of Calcium disodium edetate dihydrate?

CAS 23411-34-9; molecular formula C10H12CaN2O8.2Na; molecular weight — g/mol.

What other names is Calcium disodium edetate dihydrate known by?

Edetate calcium disodium, EDTA calcium disodium, Detoxamin, Calcium disodium ethylenediaminetetraacetate, Edetate calcium disodium anhydrous, DTXSID2036409.

What is the regulatory status of Calcium disodium edetate dihydrate?

Documented regulatory listings: FDA Regulatory Status of Color Additives: Foods, Drugs; FDA Substance added to food: ANTIOXIDANT, COLOR OR COLORING ADJUNCT, FLAVOR ENHANCER, FUMIGANT, SEQUESTRANT; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS.

Is Calcium disodium edetate dihydrate classified as hazardous?

81.1% of GHS notifications report no hazard classification (210 of 259).

What are the key physical properties of Calcium disodium edetate dihydrate?

Melting Point: >300; Color Additive Status: 73.1; Color Additive Status: 172.120; Color Additive Status: 172.135.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.