卷曲霉素

Description

Capreomycin · CAS 11003-38-6 · C50H88N28O15. UNII 232HYX66HC. LogP: -9.609.

Identification

CAS Registry Number	11003-38-6
PubChem CID	3000502
Molecular formula	C50H88N28O15
UNII (FDA)	232HYX66HC

Computed Descriptors

Molecular Weight	1321.4
Hydrogen Bond Donor Count	27
Hydrogen Bond Acceptor Count	23
Rotatable Bond Count	19
Exact Mass	1320.69839421
Monoisotopic Mass	1320.69839421
Topological Polar Surface Area	737
Heavy Atom Count	93
Formal Charge	0
Complexity	2470

Physical & Chemical Properties

LogP	-9.609

Physical description & handling notes

• White solid
• Soluble in water as disulfate salt.
• WHITE TO SLIGHTLY YELLOWISH WHITE, AMORPHOUS POWDER. ODORLESS. FREELY SOL IN WATER. PRACTICALLY INSOL IN MOST ORG SOLVENTS. /STERILE SULFATE SALT/
• Practically insol in most org solvents
• STABLE IN AQ SOLN @ PH 4-8; UNSTABLE IN STRONGLY ACIDIC OR STRONGLY BASIC SOLN /MIXT/
• SOLN DARKEN WITH NO LOSS OF POTENCY OR INCR IN TOXICITY; PROTECT FROM HEAT & MOISTURE /STERILE SULFATE SALT/

Documented Uses

• Active against strains of Mycobacterium tuberculosis found in humans
• THERAP CAT: Antibacterial (tuberculostatic)
• ... second-line injectable anti-tuberculosis drug
• ... Produced by Streptomyces capreolus
• Mixture of capreomycins IA, IB, IIA, and IIB in the approx percentages, 25%, 67%, 3%, and 6%.
• Polypeptide antibiotic isolated from Streptomyces capreolus ... complex of 4 microbiologically active components which have been characterized in part; however, complete structural determination of all components has not been established /Sulfate/

Synonyms

Capostatin; Capreomicin; Capreomicina; Capreomycine; Capromycin; Capreomycin Complex; RefChem:123292; CHEBI:3371; DTXSID8040989; J04AB30; 11003-38-6; 232HYX66HC; Capastat; capreomycin; Capreomycinum; Kapreomycin

Frequently Asked Questions

What are the CAS number and molecular formula of Capreomycin?

CAS 11003-38-6; molecular formula C50H88N28O15; molecular weight — g/mol.

What other names is Capreomycin known by?

Capostatin, Capreomicin, Capreomicina, Capreomycine, Capromycin, Capreomycin Complex.

What are the key physical properties of Capreomycin?

LogP: -9.609.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.