新戊酸氯可龙

Description

9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate · CAS 34097-16-0 · C27H36ClFO5. UNII QBL8IZH14X.

Identification

CAS Registry Number	34097-16-0
PubChem CID	5282493
Molecular formula	C27H36ClFO5
IUPAC name	[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17S)-9-chloro-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
UNII (FDA)	QBL8IZH14X

Computed Descriptors

Molecular Weight	495.0
XLogP3	4.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	494.2235301
Monoisotopic Mass	494.2235301
Topological Polar Surface Area	80.7
Heavy Atom Count	34
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H360 (96%), H372 (96%)

Documented Uses

• Breast Feeding; Lactation; Corticosteroids, Topical
• A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
• Corticosteroid Hormone Receptor Agonists [MoA]; Corticosteroid [EPC]

Synonyms

CLOCORTOLONE PIVALATE; 34097-16-0; Cloderm; Clocortolone 21-pivalate; SH 863; DTXSID0045460; QBL8IZH14X; 9-Chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate; SH-863; DTXCID8025460; CHEBI:59583; 9-chloro-6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate; clocortolone trimethylacetate; RefChem:57257; 251-826-5; 9 alpha-chloro-6 alpha-fluoro-11 beta,21-dihydroxy-16 alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate

Frequently Asked Questions

What are the CAS number and molecular formula of 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate?

CAS 34097-16-0; molecular formula C27H36ClFO5; molecular weight — g/mol.

What other names is 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate known by?

CLOCORTOLONE PIVALATE, 34097-16-0, Cloderm, Clocortolone 21-pivalate, SH 863, DTXSID0045460.

Is 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate classified as hazardous?

Hazard statements reported: H360, H372.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.