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Cidofovir hydrate (1:2)

CAS 149394-66-1C8H14N3O6PMW 279.19

Cidofovir hydrate (1:2) (CAS No. 149394-66-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number149394-66-1
Molecular FormulaC8H14N3O6P
Molecular Weight279.19
Melting Point480
LogP-3.9
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Cidofovir hydrate (1:2)?

The CAS number of Cidofovir hydrate (1:2) is 149394-66-1.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Cidofovir hydrate (1:2)?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Cidofovir hydrate (1:2) or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Cidofovir hydrate (1:2) · CAS 149394-66-1 · C8H14N3O6P. UNII 768M1V522C. Melting Point: 480; Melting Point: 260 °C (dec); Melting Point: 480 °C.

Identification

CAS Registry Number149394-66-1
PubChem CID60613
Molecular formulaC8H14N3O6P
IUPAC name[(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid
UNII (FDA)768M1V522C

Computed Descriptors

Molecular Weight279.19
XLogP3-3.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass279.06202217
Monoisotopic Mass279.06202217
Topological Polar Surface Area146
Heavy Atom Count18
Formal Charge0

Physical & Chemical Properties

Melting Point480
Melting Point260 °C (dec)
Melting Point480 °C
Solubility=170 mg/mL at pH 6-8
Solubility1.15e+01 g/L
LogP-3.9
LogP-3.17

Physical description & handling notes

  • Solid
  • Fluffy white powder
  • White crystalline powder
  • Aqueous solubility >=170 mg/ml @ pH 6-8
  • log Kow = -3.3 @ pH 7.1
  • It is recommended that cidofovir admixtures be administered within 24 hours of preparation and that refrigeration or freezer storage not be used to extend this 24 hour limit.

Documented Uses

  • Preparation: A. Holy et al., EP 253412; eidem, US 5142051 (1988, 1992 both to Ceskoslov. Akad, Ved; Rega Inst.) ... .
  • For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS)
  • Cidofovir is a nucleoside analogue and antiviral agent which is used in therapy of serious cytomegalovirus infections in immunocompromised patients. Cidofovir has been associated with mild-to-moderate serum aminotransferase elevations during intravenous therapy, but has not been convincingly linked to cases of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents
  • Cidofovir is used for the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS).
  • Cidofovir has been used for the management of acyclovir-resistant herpes simplex virus (HSV-1 and HSV-2) infections in immunocompromised patients.

Synonyms

Cidofovir; 113852-37-2; Vistide; HPMPC; Cidofovir anhydrous; (S)-HPMPC; anhydrous cidofovir; GS-504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; DTXSID3043734; GS 0504; GS504; GS-0504; 768M1V522C; NSC-742135; 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine

Frequently Asked Questions

What are the CAS number and molecular formula of Cidofovir hydrate (1:2)?

CAS 149394-66-1; molecular formula C8H14N3O6P; molecular weight — g/mol.

What other names is Cidofovir hydrate (1:2) known by?

Cidofovir, 113852-37-2, Vistide, HPMPC, Cidofovir anhydrous, (S)-HPMPC.

What are the key physical properties of Cidofovir hydrate (1:2)?

Melting Point: 480; Melting Point: 260 °C (dec); Melting Point: 480 °C; Solubility: =170 mg/mL at pH 6-8.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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