盐酸多佐洛胺

Description

Dorzolomide hydrochloride · CAS 130693-82-2 · C10H17ClN2O4S3. UNII QZO5366EW7.

Identification

CAS Registry Number	130693-82-2
PubChem CID	6918132
Molecular formula	C10H17ClN2O4S3
IUPAC name	(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride
UNII (FDA)	QZO5366EW7

Computed Descriptors

Molecular Weight	360.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	3
Exact Mass	360.0038982
Monoisotopic Mass	360.0038982
Topological Polar Surface Area	151
Heavy Atom Count	20
Formal Charge	0
Complexity	534

GHS Hazard Classification

Reported hazard statements	H302 (100%), H373 (92.1%)

Documented Uses

• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES.
• Carbonic Anhydrase Inhibitor [EPC]; Carbonic Anhydrase Inhibitors [MoA]
• Carbonic Anhydrase Inhibitors [MoA]; Carbonic Anhydrase Inhibitor [EPC]
• DORZOLAMIDE HYDROCHLORIDE OPHTHALMIC

Synonyms

DORZOLAMIDE HYDROCHLORIDE; 130693-82-2; Dorzolamide HCl; DTXSID1045530; Dorzolamide (as hydrochloride); QZO5366EW7; DTXCID9025530; CHEBI:4703; Dorzolamide PF; Dorzolamide HCI; RefChem:57215; Dorzolamide Hydrochloride Ophthalmic; Dorzolomide hydrochloride; Trusopt; Cosopt; (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Dorzolomide hydrochloride?

CAS 130693-82-2; molecular formula C10H17ClN2O4S3; molecular weight — g/mol.

What other names is Dorzolomide hydrochloride known by?

DORZOLAMIDE HYDROCHLORIDE, 130693-82-2, Dorzolamide HCl, DTXSID1045530, Dorzolamide (as hydrochloride), QZO5366EW7.

Is Dorzolomide hydrochloride classified as hazardous?

Hazard statements reported: H302, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.