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Darunavir

CAS 206361-99-1C27H37N3O7SMW 547.7

Darunavir (CAS No. 206361-99-1) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number206361-99-1
Molecular FormulaC27H37N3O7S
Molecular Weight547.7
Melting Point74-76
LogP1.89
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Darunavir?

The CAS number of Darunavir is 206361-99-1.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Darunavir?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Darunavir or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Darunavir · CAS 206361-99-1 · C27H37N3O7S. UNII YO603Y8113. Melting Point: 74-76; Melting Point: 74 °C (decomposes); Solubility: 6.68e-02 g/L.

Identification

CAS Registry Number206361-99-1
PubChem CID213039
Molecular formulaC27H37N3O7S
IUPAC name[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
UNII (FDA)YO603Y8113

Computed Descriptors

Molecular Weight547.7
XLogP32.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count12
Exact Mass547.23522170
Monoisotopic Mass547.23522170
Topological Polar Surface Area149
Heavy Atom Count38
Formal Charge0

Physical & Chemical Properties

Melting Point74-76
Melting Point74 °C (decomposes)
Solubility6.68e-02 g/L
LogP1.89
LogP1.8

Physical description & handling notes

  • Solid
  • White, amorphous solid
  • Approximately 0.15 mg/mL at
  • 11.43±0.46(Predicted)
  • Darunavir is an inhibitor of the human immunodeficiency virus (HIV) protease, which prevents HIV viral replication. When administered with ritonavir in combination antiretroviral therapy, darunavir significantly decreases viral load and increases CD4 cell counts, decreasing the morbidity and mortality of HIV infection.
  • Oral: Tablets, film-coated 300 mg (of darunavir) Prezista (Tibotec); 600 mg (of darunavir) Prezista (Tibotec).

GHS Hazard Classification

Reported hazard statementsH315 (100%), H317 (100%), H319 (100%), H335 (100%)

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

Documented Uses

  • Inhibitor of the HIV-1 protease
  • THERAPEUTIC CATEGORY: Antiviral
  • Use (kg; approx.) in Germany (2009): >750
  • Consumption (g per capita; approx.) in Germany (2009): 0.00916
  • Darunavir, co-administered with ritonavir, and with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV) in children age 3 or above and adults with HIV-1 infection.
  • Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; HIV Protease Inhibitors

Synonyms

Darunavir; 206361-99-1; TMC114; TMC-114; UIC-94017; Darunavirum; TMC 114; (-)-DARUNAVIR; DTXSID0046779; UIC 94017; CHEBI:367163; TMC-41629; YO603Y8113; DTXCID8026779; Ethanolate, Darunavir; RefChem:585195

Frequently Asked Questions

What are the CAS number and molecular formula of Darunavir?

CAS 206361-99-1; molecular formula C27H37N3O7S; molecular weight — g/mol.

What other names is Darunavir known by?

Darunavir, 206361-99-1, TMC114, TMC-114, UIC-94017, Darunavirum.

Is Darunavir classified as hazardous?

Hazard statements reported: H315, H317, H319, H335.

What are the key physical properties of Darunavir?

Melting Point: 74-76; Melting Point: 74 °C (decomposes); Solubility: 6.68e-02 g/L; LogP: 1.89.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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