diethylcarbamazine

Description

diethylcarbamazine · CAS 90-89-1 · C10H21N3O. UNII V867Q8X3ZD. Melting Point: 150-155; Melting Point: 48 °C; Solubility: 63.7.

Identification

CAS Registry Number	90-89-1
PubChem CID	3052
Molecular formula	C10H21N3O
IUPAC name	N,N-diethyl-4-methylpiperazine-1-carboxamide
UNII (FDA)	V867Q8X3ZD

Computed Descriptors

Molecular Weight	199.29
XLogP3	0.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	199.168462302
Monoisotopic Mass	199.168462302
Topological Polar Surface Area	26.8
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	150-155
Melting Point	48 °C
Solubility	63.7
Solubility	2.36e+02 g/L
LogP	0.1

Physical description & handling notes

• Solid
• 150.26 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 143.8 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 154.55 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements.

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-: INACTIVE
• Used for the treatment of certain filarial diseases, including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
• Oral - Solid: 50 mg tablet (dihydrogen citrate); 100 mg tablet (dihydrogen citrate)
• Pharmacological agents destructive to nematodes in the superfamily Filarioidea.
• Compounds that bind to and inhibit that enzymatic activity of LIPOXYGENASES. Included under this category are inhibitors that are specific for lipoxygenase subtypes and act to reduce the production of LEUKOTRIENES.
• Established Pharmacologic Class [EPC] - Anthelmintic

Synonyms

diethylcarbamazine; 90-89-1; Carbamazine; N,N-Diethyl-4-methyl-1-piperazinecarboxamide; 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-; Dietilcarbamazina; Diaethylcarbamazinum; Camin; Diethylcarbamazinum; V867Q8X3ZD; CHEBI:4527; DTXSID1022928; RefChem:587348; Maleate, Diethylcarbamazine; ditrazinum (for the citrate); DTXCID802928

Frequently Asked Questions

What are the CAS number and molecular formula of diethylcarbamazine?

CAS 90-89-1; molecular formula C10H21N3O; molecular weight — g/mol.

What other names is diethylcarbamazine known by?

diethylcarbamazine, 90-89-1, Carbamazine, N,N-Diethyl-4-methyl-1-piperazinecarboxamide, 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, Dietilcarbamazina.

Is diethylcarbamazine classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of diethylcarbamazine?

Melting Point: 150-155; Melting Point: 48 °C; Solubility: 63.7; Solubility: 2.36e+02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.