demecarium bromide

Description

demecarium bromide · CAS 56-94-0 · C32H52Br2N4O4. UNII 61D5V4OKTP. Other Experimental Properties: DECOMP @ 162-167 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• WHITE POWDER
• SLIGHTLY YELLOW, CRYSTALLINE POWDER
• FREELY SOL IN WATER, ALCOHOL; SPARINGLY SOL IN ACETONE; INSOL IN ETHER
• AQ SOLN ARE STABLE
• STABLE TO AUTOCLAVING, & RETAIN THEIR POTENCY FOR PROLONGED PERIODS
• AQ SOLN ARE NEUTRAL

GHS Hazard Classification

Documented Uses

• N,N'-DIMETHYL-1,10-DECAMETHYLENEDIAMINE IS ADDED TO MOLTEN 3-(DIMETHYLAMINO)PHENYL CARBONATE TO PRODUCE 1,10-DE CAMETHYLENEBIS[3-(DIMETHYL-AMINO)PHENYL N-METHYLCARBAMATE]. AFTER PURIFICATION THIS ESTER...A VISCOUS OIL, IS DISSOLVED IN ETHANOL & DOUBLY QUATERNIZED WITH AID OF AN ACETONE SOLN OF METHYL BROMIDE.
• SCHMID, US PATENT 2,789,981 (1957 TO OESTERREICHISCHE STICKSTOFFWERKE).
• Cholinesterase Inhibitors; Miotics
• /IN TREATMENT OF ESOTROPIA/ THERAPY SHOULD BE DISCONTINUED AFTER 4 MO IF INSTILLATION AS OFTEN AS EVERY 2 DAYS IS STILL REQUIRED.
• /CONGESTIVE IRITIS, IRIDOCYCLITIS, & CONJUNCTIVAL & INTRAOCULAR HYPEREMIA/ ... CAN BE MINIMIZED BY INSTILLATION OF SOLN OF LOWEST EFFECTIVE CONCN @ BEDTIME, & THEY OFTEN SUBSIDE AFTER FIRST FEW DAYS OF THERAPY. INSTILLATION OF 10% PHENYLEPHRINE HYDROCHLORIDE SOLN MAY BE HELPFUL IF CIRCUMCORNEAL INJECTION IS SEVERE.
• FOLLOWING INSTILLATION OF DEMECARIUM IN EYE, MIOSIS APPEARS WITHIN 1 HR & REACHES ITS MAX IN 2 TO 4 HR. REDUCTION OF INTRAOCULAR PRESSURE OCCURS IN CA 12 HR & IS FREQUENTLY PRECEDED BY SLIGHT RISE IN PRESSURE. PUPILLARY CONSTRICTION & DECR INTRAOCULAR PRESSURE MAY PERSIST FOR WK OR MORE FOLLOWING SINGLE INSTILLATION.

Synonyms

DEMECARIUM BROMIDE; 56-94-0; Humorsol; Frumtosnil; Visumiotic; Tonilen; Tosmicil; Tosmilene; Visumatic; Bromuro de demecario; Bromure de demecarium; Demekastigmine bromide; Demecarii bromidum; Demekarium bromide; BC 48; 61D5V4OKTP

Frequently Asked Questions

What are the CAS number and molecular formula of demecarium bromide?

CAS 56-94-0; molecular formula C32H52Br2N4O4; molecular weight — g/mol.

What other names is demecarium bromide known by?

DEMECARIUM BROMIDE, 56-94-0, Humorsol, Frumtosnil, Visumiotic, Tonilen.

Is demecarium bromide classified as hazardous?

Hazard statements reported: H300.

What are the key physical properties of demecarium bromide?

Other Experimental Properties: DECOMP @ 162-167 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.