des-gly10,(D-his(bzl)6)-lh-rh*ethylamide

Name: des-gly10,(D-his(bzl)6)-lh-rh*ethylamide
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 76712-82-8C66H86N18O12MW 1323.5

des-gly10,(D-his(bzl)6)-lh-rh*ethylamide (CAS No. 76712-82-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number76712-82-8

Molecular FormulaC66H86N18O12

Molecular Weight1323.5

LogP0.7

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide?

The CAS number of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide is 76712-82-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy des-gly10,(D-his(bzl)6)-lh-rh*ethylamide or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

des-gly10,(D-his(bzl)6)-lh-rh*ethylamide · CAS 76712-82-8 · C66H86N18O12. UNII H50H3S3W74. Solubility: 10.

Identification

CAS Registry Number	76712-82-8
PubChem CID	25077993
Molecular formula	C66H86N18O12
UNII (FDA)	H50H3S3W74

Computed Descriptors

Molecular Weight	1323.5
XLogP3	0.7
Hydrogen Bond Donor Count	15
Hydrogen Bond Acceptor Count	15
Rotatable Bond Count	34
Exact Mass	1322.66726025
Monoisotopic Mass	1322.66726025
Topological Polar Surface Area	449
Heavy Atom Count	96
Formal Charge	0

Physical & Chemical Properties

Solubility	10

Physical description & handling notes

Specific optical rotation = -33.9 deg at 20 °C/D ( c = 1 in acetic acid)
5.3 (His-base)
Histrelin acetate formulations: Parenteral implants, 50 mg histrelin acetate, Vanta by Valera.

GHS Hazard Classification

Reported hazard statements	H360 (100%)

H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

Documented Uses

Palliative treatment of advanced prostate cancer
Treatment of children with central precocious puberty
THERAP CAT: Treatment of central precocious puberty
J.E.F. Rivier, W.W. Vale Jr., EP 21620; eidem, US 4244946 (both 1981 to Salk Institute)
Synthetic nonapeptide agonist analog of LH-RH.
As the product Supprelin LA (FDA), histrelin is indicated for the treatment of children with central precocious puberty (CPP). As the product Vantas (FDA), histrelin is indicated for the palliative treatment of advanced prostate cancer.

Synonyms

histrelin; 76712-82-8; Histrelina; Histreline; Histrelinum; ORF 17070; RWJ 17070; ORF-17070; H50H3S3W74; RWJ-17070; ((ImBl)-D-His(sub 6),Pro(sub 9)-NEt)LHRH; ORF 17070RWJ 17070; CHEBI:5739; DTXSID50227543; IBHPE-LHRH; RefChem:56340

Frequently Asked Questions

What are the CAS number and molecular formula of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide?

CAS 76712-82-8; molecular formula C66H86N18O12; molecular weight — g/mol.

What other names is des-gly10,(D-his(bzl)6)-lh-rh*ethylamide known by?

histrelin, 76712-82-8, Histrelina, Histreline, Histrelinum, ORF 17070.

Is des-gly10,(D-his(bzl)6)-lh-rh*ethylamide classified as hazardous?

Hazard statements reported: H360.

What are the key physical properties of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide?

Solubility: 10.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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