东甲三唑三硅氧烷

Description

DROMETRIZOLE TRISILOXANE · CAS 155633-54-8 · C24H39N3O3Si3. UNII HC22845I1X.

Identification

CAS Registry Number	155633-54-8
PubChem CID	9848888
Molecular formula	C24H39N3O3Si3
IUPAC name	2-(benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[methyl-bis(trimethylsilyloxy)silyl]propyl]phenol
UNII (FDA)	HC22845I1X

Computed Descriptors

Molecular Weight	501.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	9
Exact Mass	501.22992172
Monoisotopic Mass	501.22992172
Topological Polar Surface Area	69.4
Heavy Atom Count	33
Formal Charge	0
Complexity	613

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Uv absorber
GHS notification summary	100% (4 / 4)

GHS Hazard Classification

GHS notification summary	100% (4 / 4)

Documented Uses

• Drometrizole trisiloxane is used as an active ingredient in various sunscreens for the indication of protecting the skin by absorbing the damaging UV radiation of sunlight.
• Drometrizole trisiloxane is reported as having little to no absorption through the skin. At this time, however, studies demonstrate that the components of most commonly used sunscreens are likely absorbed into the skin at least to some extent - although penetration to deeper tissues and the cutaneous circulation remains limited. Despite the extensive use of sunscreen products around the world, there have been few reports of adverse effects related to their use.

Synonyms

Drometrizole trisiloxane; 155633-54-8; Silatrizole; Mexoryl XL; OR 10154; OR-10154; HC22845I1X; DTXSID40431753; RefChem:135828; DTXCID30382583; 919-634-2; Drometrizole trisiloxane [WHO-DD]; 2-(benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[methyl-bis(trimethylsilyloxy)silyl]propyl]phenol; UNII-HC22845I1X; Drometrizole trisiloxane [INCI]; SCHEMBL15380

Frequently Asked Questions

What are the CAS number and molecular formula of DROMETRIZOLE TRISILOXANE?

CAS 155633-54-8; molecular formula C24H39N3O3Si3; molecular weight — g/mol.

What other names is DROMETRIZOLE TRISILOXANE known by?

Drometrizole trisiloxane, 155633-54-8, Silatrizole, Mexoryl XL, OR 10154, OR-10154.

What is the regulatory status of DROMETRIZOLE TRISILOXANE?

Documented regulatory listings: CIR / INCI: Uv absorber.

Is DROMETRIZOLE TRISILOXANE classified as hazardous?

100% of GHS notifications report no hazard classification (4 of 4).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.