Dexloxiglumide

Description

Dexloxiglumide · CAS 119817-90-2 · C21H30Cl2N2O5. UNII 69DY40RH9B.

Identification

Computed Descriptors

Documented Uses

• For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD).
• Rapidly and extensively absorbed after single oral administration in humans with an absolute bioavailability of 48%. The incomplete bioavailability is due to both incomplete absorption and hepatic first-pass effect.
• Dexloxiglumide has known human metabolites that include 4-[(3,4-Dichlorobenzoyl)amino]-5-[3-hydroxypropyl(pentyl)amino]-5-oxopentanoic acid.
• CCKA antagonists target receptors in the gastrointestinal system to increase gastric emptying and intestinal motility, as well as modulate intestinal sensitivity to distension.

Synonyms

Dexloxiglumide; 119817-90-2; Dexloxiglumida; Dexloxiglumidum; CR-2017; Loxiglumide, (r)-; 69DY40RH9B; DTXSID50152604; (R)-4-(3,4-Dichlorobenzamido)-N-(3-methoxypropyl)-N-pentylglutaramic acid; (4R)-4-((3,4-dichlorobenzoyl)amino)-5-(3-methoxypropyl-pentylamino)-5-oxopentanoic acid; (4R)-4-[(3,4-dichlorobenzoyl)amino]-5-(3-methoxypropyl-pentylamino)-5-oxopentanoic acid; Loxiglumide (r)-; RefChem:132395; DTXCID8075095; (4R)-4-((3,4-dichlorophenyl)formamido)-4-((3-methoxypropyl)(pentyl)carbamoyl)butanoic acid; (R)-4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Dexloxiglumide?

CAS 119817-90-2; molecular formula C21H30Cl2N2O5; molecular weight — g/mol.

What other names is Dexloxiglumide known by?

Dexloxiglumide, 119817-90-2, Dexloxiglumida, Dexloxiglumidum, CR-2017, Loxiglumide, (r)-.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.