Estriol

Description

Estriol · CAS 50-27-1 · C18H24O3. UNII FB33469R8E. Melting Point: 82-86; Melting Point: 288 °C (decomposes); Melting Point: 282 °C.

Identification

CAS Registry Number	50-27-1
PubChem CID	5756
Molecular formula	C18H24O3
IUPAC name	(8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol
UNII (FDA)	FB33469R8E

Computed Descriptors

Molecular Weight	288.4
XLogP3	2.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	288.17254462
Monoisotopic Mass	288.17254462
Topological Polar Surface Area	60.7
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	82-86
Melting Point	288 °C (decomposes)
Melting Point	282 °C
Density	1.27 g/cu cm at 25 °C
LogP	2.45
LogP	log Kow = 2.45

Physical description & handling notes

• Solid
• Odorless white crystals.
• Leaflets from alcohol
• Very small monoclinic crystals from dilute alcohol
• White, microcrystalline powder
• Odorless

GHS Hazard Classification

Reported hazard statements	H350 (23.9%), H351 (74.8%), H360 (97.4%), H362 (49.7%), H372 (23.9%), H410 (23.2%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >50
• Consumption (g per capita; approx.) in Germany (2009): 0.000611
• Used as a test to determine the general health of an unborn fetus.
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Isolation from pregnant human urine, isolated from human placenta, organic synthesis.
• /Estriol is indicated as/ hormone replacement therapy for treatment of atrophic vaginitis and kraurosis in post-menopausal women.

Synonyms

estriol; 50-27-1; Oestriol; Trihydroxyestrin; Aacifemine; Estratriol; Ovestrion; Tridestrin; Destriol; Ovestin; Theelol; Hormomed; Klimoral; Oestratriol; Orestin; Triovex

Frequently Asked Questions

What are the CAS number and molecular formula of Estriol?

CAS 50-27-1; molecular formula C18H24O3; molecular weight — g/mol.

What other names is Estriol known by?

estriol, 50-27-1, Oestriol, Trihydroxyestrin, Aacifemine, Estratriol.

Is Estriol classified as hazardous?

Hazard statements reported: H350, H351, H360, H362, H372.

What are the key physical properties of Estriol?

Melting Point: 82-86; Melting Point: 288 °C (decomposes); Melting Point: 282 °C; Density: 1.27 g/cu cm at 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.