ethionamide

Name: ethionamide
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 536-33-4C8H10N2SMW 166.25

ethionamide (CAS No. 536-33-4) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number536-33-4

Molecular FormulaC8H10N2S

Molecular Weight166.25

Melting Point166

LogP0.5

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of ethionamide?

The CAS number of ethionamide is 536-33-4.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of ethionamide?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy ethionamide or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

ethionamide · CAS 536-33-4 · C8H10N2S. UNII OAY8ORS3CQ. Melting Point: 166; Melting Point: 164-166 °C (decomposes); Melting Point: 163 °C.

Identification

CAS Registry Number	536-33-4
PubChem CID	2761171
Molecular formula	C8H10N2S
IUPAC name	2-ethylpyridine-4-carbothioamide
UNII (FDA)	OAY8ORS3CQ

Computed Descriptors

Molecular Weight	166.25
XLogP3	1.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	166.05646950
Monoisotopic Mass	166.05646950
Topological Polar Surface Area	71
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Melting Point	166
Melting Point	164-166 °C (decomposes)
Melting Point	163 °C
Solubility	8.39e-01 g/L
LogP	0.5
LogP	log Kow = 0.3699
LogP	1.52

Physical description & handling notes

Ethionamide appears as yellow crystals or canary yellow powder with a faint to moderate sulfide odor. (NTP, 1992)
Solid
Yellow crystals from ethanol
Faint to moderate sulfide odor
327 to 331 °F (Decomposes) (NTP, 1992)
less than 1 mg/mL at 70 °F (NTP, 1992)

GHS Hazard Classification

Reported hazard statements	H302 (95.7%), H361 (91.5%)

H302 (95.7%): Harmful if swallowed [Warning Acute toxicity, oral]

H361 (91.5%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

THERAP CAT: Antibacterial (tuberculostatic)
... Prepared by addition of hydrogen sulfide to 2-ethylnicotinonitrile in the presence of triethanolamine
For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.
Ethionamide is a second line drug in the therapy of tuberculosis used only in combination with other agents and for drug-resistant tuberculosis. Ethionamide has been linked to transient, asymptomatic elevations in serum aminotransferase levels and in uncommon instances of acute liver injury, which can be severe.
Breast Feeding; Lactation; Anti-infective Agents; Antitubercular Agents
(1) Oral - Solid - dispersible tablet: 125 mg; (2) Oral - Solid - tablet: 250 mg

Synonyms

ethionamide; 536-33-4; 2-ethylpyridine-4-carbothioamide; Trecator; Ethioniamide; Amidazine; Ethinamide; Ethyonomide; Etionamid; Etioniamid; 2-Ethylthioisonicotinamide; Nizotin; Ethylisothiamide; Teberus; Trecator-SC; Amidazin

Frequently Asked Questions

What are the CAS number and molecular formula of ethionamide?

CAS 536-33-4; molecular formula C8H10N2S; molecular weight — g/mol.

What other names is ethionamide known by?

ethionamide, 536-33-4, 2-ethylpyridine-4-carbothioamide, Trecator, Ethioniamide, Amidazine.

Is ethionamide classified as hazardous?

Hazard statements reported: H302, H361.

What are the key physical properties of ethionamide?

Melting Point: 166; Melting Point: 164-166 °C (decomposes); Melting Point: 163 °C; Solubility: 8.39e-01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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