Ergoloid Mesylates

Description

Ergoloid Mesylates · CAS 8067-24-1 · C33H45N5O5. UNII X3S33EX3KW. Melting Point: 192; LogP: 2.8.

Identification

CAS Registry Number	8067-24-1
PubChem CID	592735
Molecular formula	C33H45N5O5
IUPAC name	N-[2-hydroxy-7-(2-methylbutan-2-yl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
UNII (FDA)	X3S33EX3KW

Computed Descriptors

Molecular Weight	591.7
XLogP3	3.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	591.34206955
Monoisotopic Mass	591.34206955
Topological Polar Surface Area	118
Heavy Atom Count	43
Formal Charge	0

Physical & Chemical Properties

Melting Point	192
LogP	2.8

Physical description & handling notes

• Decomposes
• Partially soluble

GHS Hazard Classification

Reported hazard statements	H228 (57.1%), H302 (100%), H312 (14.3%), H315 (14.3%), H319 (14.3%), H332 (71.4%), H335 (14.3%), H360 (28.6%)

Documented Uses

• Take with or without food. Taking ergoloid mesylate with food may reduce gastrointestinal upset.
• Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
• Drugs used to cause dilation of the blood vessels.
• Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.
• QC04A - Peripheral vasodilators
• The ergoloid mesylate mixture is mainly excreted via bile in feces. The ratio of the eliminated dose via urine after intravenous and oral administration is 8.4% and 2% respectively. Urinary excretion of the unchanged drug is very small and bile excretion is represented mainly by ergot metabolites conformed as conjugated compounds. To know more about the individual components of the ergoloid mixture, please visit [DB11274], [DB11273] and [DB13345].

Synonyms

Alkergot; Ergoloid mesylate; Dihydroergotoxine methanesulfonate; CO-Dergocrine mesylate; dihydroergotoxine mesilate; Gerimal; Hydergine LC; Deapril-ST; Dihydroergotoxine methanesulphonate; Deapril; Redergine; DTXSID5031428; Co Dergine Mesylate; Co-Dergine Mesylate; codergocrine mesylate; Co Dergocrine Mesilate

Frequently Asked Questions

What are the CAS number and molecular formula of Ergoloid Mesylates?

CAS 8067-24-1; molecular formula C33H45N5O5; molecular weight — g/mol.

What other names is Ergoloid Mesylates known by?

Alkergot, Ergoloid mesylate, Dihydroergotoxine methanesulfonate, CO-Dergocrine mesylate, dihydroergotoxine mesilate, Gerimal.

Is Ergoloid Mesylates classified as hazardous?

Hazard statements reported: H228, H302, H312, H315, H319.

What are the key physical properties of Ergoloid Mesylates?

Melting Point: 192; LogP: 2.8.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.