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Deflazacort

CAS 14484-47-0C25H31NO6MW 441.5

Deflazacort (CAS No. 14484-47-0) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number14484-47-0
Molecular FormulaC25H31NO6
Molecular Weight441.5
Melting Point>215 C
LogP2.4
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Deflazacort?

The CAS number of Deflazacort is 14484-47-0.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Deflazacort?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Deflazacort or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Deflazacort · CAS 14484-47-0 · C25H31NO6. UNII KR5YZ6AE4B. Melting Point: >215 C; Solubility: 108; LogP: 2.4.

Identification

CAS Registry Number14484-47-0
PubChem CID189821
Molecular formulaC25H31NO6
IUPAC name[2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethyl] acetate
UNII (FDA)KR5YZ6AE4B

Computed Descriptors

Molecular Weight441.5
XLogP32
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass441.21513771
Monoisotopic Mass441.21513771
Topological Polar Surface Area102
Heavy Atom Count32
Formal Charge0

Physical & Chemical Properties

Melting Point>215 C
Solubility108
LogP2.4
Dissociation Constants5.52

Physical description & handling notes

  • 204.8 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9020378]
  • 206.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID9020378]
  • 213.4 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9020378]
  • 205.2 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID9020378]

GHS Hazard Classification

Reported hazard statementsH360 (77.4%), H361 (16.1%), H373 (93.5%)

H360 (77.4%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H361 (16.1%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Deflazacort is indicated for the treatment of Duchenne Muscular Dystrophy (DMD) in patients 2 years of age and older.
  • Breast Feeding; Lactation; Corticosteroids, Systemic; Glucocorticoids; Anti-Inflammatory Agents;
  • Deflazacort (Class: Other Substances, Added Date: 08-2025)
  • Avoid grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of deflazacort.
  • Avoid St. John's Wort. This herb induces CYP3A metabolism and may reduce serum levels of deflazacort.
  • Take with or without food. The tablets may be crushed and mixed with applesauce and consumed immediately.

Synonyms

DEFLAZACORT; 14484-47-0; Emflaza; Deflazacortum; DTXSID9020378; MDL 458; DL-458IT; L-5458; MDL-458; KR5YZ6AE4B; MDL458; DTXCID10378; 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11beta,16beta)-; 5'H-Pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-11-hydroxy-2'-methyl-, (11beta,16beta)-; Deflazacort Oral; RefChem:56797

Frequently Asked Questions

What are the CAS number and molecular formula of Deflazacort?

CAS 14484-47-0; molecular formula C25H31NO6; molecular weight — g/mol.

What other names is Deflazacort known by?

DEFLAZACORT, 14484-47-0, Emflaza, Deflazacortum, DTXSID9020378, MDL 458.

Is Deflazacort classified as hazardous?

Hazard statements reported: H360, H361, H373.

What are the key physical properties of Deflazacort?

Melting Point: >215 C; Solubility: 108; LogP: 2.4; Dissociation Constants: 5.52.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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