盐酸多奈哌齐

Name: 盐酸多奈哌齐
Brand: 济南圣和化工有限公司

CAS 120011-70-3C24H30ClNO3MW 416.0

盐酸多奈哌齐，CAS 登记号 120011-70-3，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号120011-70-3

分子式C24H30ClNO3

分子量416.0

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

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可以提供哪些规格和包装？

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盐酸多奈哌齐一般用在什么产品里？

主要涉及医药中间体及原料药。

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PubChem 公开数据

Description

Donepezil Hydrochloride · CAS 120011-70-3 · C24H30ClNO3. UNII 3O2T2PJ89D.

Identification

CAS Registry Number	120011-70-3
PubChem CID	5741
Molecular formula	C24H30ClNO3
IUPAC name	2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
UNII (FDA)	3O2T2PJ89D

Computed Descriptors

Molecular Weight	416.0
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	415.1914215
Monoisotopic Mass	415.1914215
Topological Polar Surface Area	38.8
Heavy Atom Count	29
Formal Charge	0
Complexity	510

Physical description & handling notes

196.6 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H300 (17.9%), H301 (76.2%), H319 (79.8%)

H300 (17.9%): Fatal if swallowed [Danger Acute toxicity, oral]

H301 (76.2%): Toxic if swallowed [Danger Acute toxicity, oral]

Documented Uses

For the palliative treatment of mild to moderate dementia of the Alzheimer's type.
Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.
Cholinesterase Inhibitors [MoA]; Cholinesterase Inhibitor [EPC]
Donepezil is metabolized by CYP 450 isoenzymes 2D6 and 3A4 in the liver and also undergoes glucuronidation. The main metabolite, 6-O-desmethyl donepezil, has been reported to inhibit AChE to the same extent as donepezil in vitro. Route of Elimination: Donepezil is both excreted in the urine intact and extensively metabolized to four major metabolites, two of which are known to be active, and a number of minor metabolites, not all of which have been identified. Half Life: 70 hours

Synonyms

Donepezil hydrochloride; 120011-70-3; Donepezil HCl; BNAG; Aricept ODT; E-2020; E2020; ADLARITY; DTXSID0046698; Aricept Evess; NSC-737535; NSC-758882; 3O2T2PJ89D; DTXCID8026698; 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl; NAMZARIC COMPONENT DONEPEZIL HYDROCHLORIDE

Frequently Asked Questions

What are the CAS number and molecular formula of Donepezil Hydrochloride?

CAS 120011-70-3; molecular formula C24H30ClNO3; molecular weight — g/mol.

What other names is Donepezil Hydrochloride known by?

Donepezil hydrochloride, 120011-70-3, Donepezil HCl, BNAG, Aricept ODT, E-2020.

Is Donepezil Hydrochloride classified as hazardous?

Hazard statements reported: H300, H301, H319.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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