盐酸洛哌丁胺

Description

Loperamide HCL · CAS 34552-83-5 · C29H34Cl2N2O2. UNII 77TI35393C.

Identification

CAS Registry Number	34552-83-5
PubChem CID	71420
Molecular formula	C29H34Cl2N2O2
IUPAC name	4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride
UNII (FDA)	77TI35393C

Computed Descriptors

Molecular Weight	513.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	7
Exact Mass	512.1997337
Monoisotopic Mass	512.1997337
Topological Polar Surface Area	43.8
Heavy Atom Count	35
Formal Charge	0
Complexity	623

Physical description & handling notes

• >77 [ug/mL] (The mean of the results at pH 7.4)
• 219.4 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition.
• FIRST AID DIRECT ANTI-DIARRHEAL
• Opioid Agonist [EPC]; Opioid Agonists [MoA]
• Opioid Agonists [MoA]; Opioid Agonist [EPC]

Synonyms

Loperamide hydrochloride; 34552-83-5; Loperamide HCl; Imodium A-D; Arret; Imodium A-D EZ chews; Up and up anti diarrheal; NSC-696356; DTXSID00880006; Loperamidi hydrochloridum; 4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride; 77TI35393C; R 18,553; 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide HCl; CHEBI:6533; 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Loperamide HCL?

CAS 34552-83-5; molecular formula C29H34Cl2N2O2; molecular weight — g/mol.

What other names is Loperamide HCL known by?

Loperamide hydrochloride, 34552-83-5, Loperamide HCl, Imodium A-D, Arret, Imodium A-D EZ chews.

Is Loperamide HCL classified as hazardous?

Hazard statements reported: H301.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.